Actinomyces naeslundii causing pulmonary endobronchial Actinomycosis – A case report

Harisree, S; Supriya, B R; Savio, Jayanthi; Ramachandran, Priya

doi:10.4103/ijpm.ijpm_706_17

Cited by 9 publications

(3 citation statements)

References 2 publications

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“…It indicated right-sided empyema and/or breast or pleural neoplasm. According to the literature, pulmonary Other observations include cavitation within the nodular infiltrates, central necrosis, ground-glass opacities, subpleural consolidation, mediastinal lymph nodes enlargement, pleural thickening and effusion [1,7]. At that stage, it is very difficult to differentiate actinomycosis from pulmonary tuberculosis, neoplasms, lung abscesses or fungal lesions.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, high doses of antibiotics and prolonged time of treatment should be applied. Standard treatment regimen includes the use of intravenous penicillin (18-24 mln units/day) for 2 to 6 weeks followed by oral treatment for 6 to 12 months (amoxicillin 3 g/day) [1,4,10]. Alternative treatments are based on the use of clindamycin or macrolides.…”

Section: Discussionmentioning

confidence: 99%

“…Actinomycosis is a rare disease caused by Actinomyces spp., gram-positive anaerobic bacteria that normally live in the human oral cavity, digestive tract and urogenital system as commensals. A. israelli is considered to be the most common cause of the disease, followed by A. naeslundi and A. mayeari [1]. These bacteria usually coexist with other microorganisms that reduce the oxygen concentration in the environment and weaken the body defences, allowing Actinomyces to grow [2].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pulmonary Actinomycosis Complicated by Fistula of the Chest Wall

Łyżwa¹,

Siemion-Szcześniak²,

Sobiecka³

et al. 2021

Advances in Respiratory Medicine

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Actinomycosis is a rare disease caused by Actinomyces spp. The clinical and radiological picture of the disease is uncharacter-istic, which delays the diagnosis and can lead to complications. We present a case of pulmonary actinomycosis complicated by a chest wall fistula in a 43-year-old man with advanced tooth decay. The patient was admitted to our Department due to a chest wall fistula with bloody discharge. A few months earlier, he was treated with antibiotics for pneumonia. Since then, weakness, exertional dyspnoea, and weight loss had been observed. On admission, increased inflammatory markers were found in laboratory tests. Chest computed tomography (CT) revealed right-sided encapsulated pleural fluid collection containing gas bubbles, pleural thickening, anterior thoracic wall soft tissues thickening and subcutaneous fat stranding. CT suggested an empyema or a breast either pleural malignancy. The picture suggested a breast or pleural tumour to differentiate with an empyema. Videothoracoscopy was performed, the histological examination of the collected samples revealed granulation tissue and bacterial colony of a morphology corresponding to Actinomyces spp. Pulmonary actinomycosis was diagnosed. Antibiotic therapy according to the Guideliness was initiated and dental treatment was recommended. Healing of the fistula and significant regression of lesions in the right lung were achieved. Although it is a rare disease, actinomycosis should be considered in the differential diagnosis of any chronic infiltrative lung lesions.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%