Actinomycosis: Some Concepts of Therapy and Prognosis

Fisher, Aaron; Harvey, John Collins

doi:10.1080/00325481.1956.11708235

Cited by 19 publications

(5 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Typical management of cervicofacial actinomycosis consists of conservative debridement and aggressive intravenous antibiotic therapy lasting several months. In most instances, with this regimen, the disease can be well controlled, and even cured [3] , [5] .…”

Section: Discussionmentioning

confidence: 99%

“…Actinomyces species are anaerobic filamentous Gram-positive bacteria that are commensal organisms in the human mouth, digestive, and genital tracts [1] , [2] . However, these organisms can become pathological, particularly in patients with risk factors such as poor oral hygiene, history of mucosal breach or trauma, male gender, diabetes, immunosuppression, alcoholism, and malnutrition [1] , [3] . Cervicofacial actinomycosis describes osteomyelitis of the facial skeleton related to actinomycosis and may involve deformity and abscess formation, most frequently affecting the mandible [4] .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Craniofacial Actinomyces osteomyelitis evolving from sinusitis

Shen

Futran

Sardesaı

2018

Radiology Case Reports

View full text Add to dashboard Cite

Craniofacial Actinomyces osteomyelitis progression is rare, as patients are soon treated. A 56-year-old male smoker presented with sinusitis and was managed medically. This patient failed to follow up and presented 1 year later with erosive bony disease. He was managed medically and surgically; however, his disease evolved to include his midface, skull base, and cranium. He underwent staged debridement and free tissue reconstruction. His disease is controlled but not cured. The literature includes case reports and small series describing limited disease treated successfully with surgical and medical management. Although craniofacial Actinomyces osteomyelitis is uncommon, it can become debilitating. This case demonstrates how craniofacial Actinomyces osteomyelitis can progress and highlights the benefit of a multidisciplinary approach.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Craniofacial Actinomyces osteomyelitis evolving from sinusitis

Shen

Futran

Sardesaı

2018

Radiology Case Reports

View full text Add to dashboard Cite

show abstract

“…18 Since its first description in the 1950s, treatment for actinomycosis as described by Fisher et al and Garrod has not significantly changed. 20,21 The standard remains penicillin, but case reports and clinical experience has shown that tetracycline and clindamycin are acceptable alternatives, especially in the setting of penicillin allergy. [2][3][4]7,22 Although originally recommended treatment duration ranged from 6 to 12 months, recent literature suggests that not all cases warrant long-term antibiotics.…”

Section: Discussionmentioning

confidence: 99%

“…Since its first description in the 1950s, treatment for actinomycosis as described by Fisher et al and Garrod has not significantly changed 20, 21. The standard remains penicillin, but case reports and clinical experience has shown that tetracycline and clindamycin are acceptable alternatives, especially in the setting of penicillin allergy 2–4, 7, 22.…”

Section: Discussionmentioning

confidence: 99%

Invasive sinonasal actinomycosis

Vorasubin

Day

et al. 2012

The Laryngoscope

View full text Add to dashboard Cite

Actinomycosis is a rare anaerobic bacterial infection typically caused by Actinomyces israelii. Although part of normal flora in the oral cavity, and respiratory and digestive tracts, A israelii can give rise to pathologic infections most commonly reported in the oral cavity from odontogenic causes. We present a rare case of invasive actinomycosis presenting with extensive midface destruction involving the maxilla and paranasal sinuses, with mucosal necrosis mimicking an aggressive neoplasm. The diagnosis is usually reached only after histopathologic analysis showing characteristic sulfur granules with filamentous gram-positive, non-acid-fast bacteria. We review the literature on its epidemiology, clinical presentation, diagnosis, treatment, and prognosis.

show abstract

“…Aktinomikozun tedavisinde en başarılı sonuçlar penisilin G ile elde edilmektedir (2). Servikofasiyal aktinomikozlu olguların tedavisinin 12-18 aylık penisilin tedavisine ek olarak cerrahi debridmanla yapılacağı ilk kez 1956'da bildirilmiştir (27). Sudhakar ve Ross (28) ise 2004 yılında sundukları çalışmada 6 haftalık bir medikal tedavinin yeterli olacağını bildirmişlerdir.…”

Section: İrdelemeunclassified