Actinomycotic Brain Abscess and Subdural Empyema of Odontogenic Origin: Case Report and Review of the Literature

Haggerty, Christopher J.; Tender, Gabriel C.

doi:10.1016/j.joms.2011.09.035

Cited by 26 publications

(26 citation statements)

References 24 publications

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“…[ 13 ] In addition, histopathological diagnosis of actinomycosis is difficult because tissue specimens typically contain few sulfur granules and because cultures are negative in up to 70% cases. [ 9 , 12 , 16 ] Therefore, final diagnosis should be made based on clinical findings in combination with microbiological and/ or histopathological findings. Because of its rarity, a universally accepted classification system for this infection is unavailable, leading to several opinions regarding the origin, diagnosis, management, and treatment outcomes.…”

Section: Discussionmentioning

confidence: 99%

Brain abscess caused by chronic invasive actinomycosis in the nasopharynx

et al. 2018

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Rationale:Actinomycosis is a rare anaerobic, gram-positive bacterial infection caused by Actinomyces, which is part of the normal flora in the oral cavity and respiratory and female genitourinary tracts. The cervicofacial area is the most common site of involvement, and involvement of the central nervous system is rare.Patient concerns:We report a case involving a 51-year-old woman who developed an actinomycotic brain abscess 15 months after the treatment of noninvasive nasopharyngeal actinomycosis, which recurred as an invasive form.Diagnoses:Histopathological examination of the surgical specimens revealed actinomycosis.Interventions:The patient was treated by surgical drainage of the brain abscess and long-term antibiotic treatment.Outcomes:Follow-up brain imaging performed 12 months after surgery showed complete resolution of the brain abscess, and there were no further signs or symptoms of infection.Lessons:Physicians should be aware of the typical clinical presentations of cervicofacial actinomycosis. Moreover, they should know that actinomycosis may mimic the process of malignancy at various anatomical locations.

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Section: Discussionmentioning

confidence: 99%

Brain abscess caused by chronic invasive actinomycosis in the nasopharynx

et al. 2018

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“…For instance, the literature describes many cases of dental infections complicated with serious pathologies. Haggerty CJ, DDS, MD,* and Tender GC, MD† J showed a case of subdural empyema of odontogenic origin caused by Actinomycotic infection ( 4 ). Santana-Cabrera L, Rodríguez-Escot C, Eugenio-Robaina P and Sánchez-Palacios M reported a case of Orbital cellulitis and subdural empyema as a complication of tooth extraction.…”

Section: Discussionmentioning

confidence: 99%

Meningitis and subdural empyema as complication of pterygomandibular space abscess upon tooth extraction

Cariati¹,

Cabello-Serrano²,

Monsalve-Iglesias³

et al. 2016

J Clin Exp Dent

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Complication of dental infections might be various and heterogeneous. The most common complications are represented by maxilar celulitis, canine space celulitis, infratemporal space celulitis, temporal celulitis and bacteremia. Among rarest complications we found: sepsis, bacterial endocarditis, mediastinitis, intracranial complications, osteomyelitis, etc. Although dental infections are often considered trivial entities, sometimes they can reach an impressive gravity. In this regard, the present study describes a case of dental infection complicated by meningitis, subdural empiema and cerebral vasculitis. Furthermore, we observed other neurological complications, like thalamic ischemic infarction, during the disease evolution. Noteworthy, these entities were not presented when the patient was admitted to hospital. Therefore, the main aim of this report is to highlight the serious consequences that an infection of dental origin could cause. Key words:Meningitis, subdural empyema, odontogenic infections.

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“…Previous case reports have suggested a duration of 3–12 months of therapy for the most severe infections 8. One case report describes a patient with a history of chronic ethanol abuse who was non-compliant with oral antibiotics following a 6-week course of parenteral antibiotics.…”

Section: Discussionmentioning

confidence: 99%

“…One case report describes a patient with a history of chronic ethanol abuse who was non-compliant with oral antibiotics following a 6-week course of parenteral antibiotics. Despite this, CT imaging 6 months later showed resolution of multiple cerebral abscesses 8. A case series reviewing 26 cases of A. meyeri infection reported between 1960 and 1995 found that the mean duration of therapy was 6 months.…”

Section: Discussionmentioning

confidence: 99%

Actinomyces meyeribrain abscess following dental extraction

Clancy¹,

Ronayne

Prentice

et al. 2015

BMJ Case Reports

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We describe the rare occurrence of an Actinomyces meyeri cerebral abscess in a 55-year-old woman following a dental extraction. This patient presented with a 2-day history of hemisensory loss, hyper-reflexia and retro-orbital headache, 7 days following a dental extraction for apical peridonitis. Neuroimaging showed a large left parietal abscess with surrounding empyema. The patient underwent craniotomy and drainage of the abscess. A. meyeri was cultured. Actinomycosis is a rare cause of cerebral abscess. The A. meyeri subtype is particularly rare, accounting for less than 1% of specimens. This case describes an unusually brief course of the disease, which is usually insidious. Parietal lobe involvement is unusual as cerebral abscesses usually have a predilection for the frontal and temporal regions of the brain. Although there are no randomised trials to guide therapy, current consensus is to use a prolonged course of intravenous antibiotics, followed by 6-12 months of oral therapy.

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Actinomycotic Brain Abscess and Subdural Empyema of Odontogenic Origin: Case Report and Review of the Literature

Cited by 26 publications

References 24 publications

Brain abscess caused by chronic invasive actinomycosis in the nasopharynx

Brain abscess caused by chronic invasive actinomycosis in the nasopharynx

Meningitis and subdural empyema as complication of pterygomandibular space abscess upon tooth extraction

Actinomyces meyeribrain abscess following dental extraction

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