Activation in the Hypothalamic–Pituitary–Adrenocortical Axis and Sympathetic Nervous System in Women with Carpal Tunnel Syndrome

Abstract

These results suggest that women with severe CTS exhibit changes in activation in the HPA axis and SNS but not in the humoral immune system. Activation of the SNS was associated with the intensity of pain. Future studies are needed to elucidate the direction of this relationship.