Activation of glassy carbon electrodes by alternating current electrochemical treatment

Wang, Joseph; Hutchins, L.D.

doi:10.1016/s0003-2670(00)84435-9

Cited by 99 publications

(40 citation statements)

References 17 publications

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“…However, it is known that the accumulation of reaction products and thus the fouling effect of the electrode surface make a serious hindrance when catecholamines are oxidized directly at the bare electrode surfaces [3]. Moreover, catecholamines exist in natural environment together with some small biomolecules like ascorbic acid (AA) and uric acid (UA), which oxidize at bare electrodes in almost the same potential region as catecholamine [4][5][6][7][8][9][10]. In recent years, among various attempts to overcome the abovementioned problems much attention has been paid to the use of electrodes modified for development of suitable sensors.…”

Section: Introductionmentioning

confidence: 99%

Electroanalysis of Norepinephrine at Bare Gold Electrode Pure and Modified with Gold Nanoparticles and S‐Functionalized Self‐Assembled Layers in Aqueous Solution. Part II

Łuczak¹

2010

Electroanalysis

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Gold electrodes modified with S-containing compounds and gold were used for determination of norepinephrine (NEP) in aqueous solution. A linear relationship between norepinephrine concentration and current response was obtained in the range of 0.1 mM to 600 mM with the detection limit 0.090 mM for the electrodes modified at 2D template and in the range of 0.1 mM to 700 mM with the detection limit 0.075 mM for the electrodes modified at 3D template. The results have shown that modified electrodes could clearly resolve the oxidation peaks of norepinephrine, ascorbic (AA) and uric acid (UA) with peak-to-peak separation enabling determination of NEP, AA and UA in the presence of each other.

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Section: Introductionmentioning

confidence: 99%

Electroanalysis of Norepinephrine at Bare Gold Electrode Pure and Modified with Gold Nanoparticles and S‐Functionalized Self‐Assembled Layers in Aqueous Solution. Part II

Łuczak¹

2010

Electroanalysis

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“…Even though the concept is presented in terms of ADH, it could be extended to many other NAD+-dependent dehydrogenases. Other methods for electrochemical pretreatment (e.g., potentiostatic and galvanostatic pulses [5,6]), as well as other activation schemes (e.g., vacuum or laser treatments), may be found useful for improving the performance of amperometric biosensors based on other enzymes or transducing carbon surfaces ( e g , oxidases or graphite, respectively).…”

Section: Resultsmentioning

confidence: 99%

Amperometric biosensing of alcohols at electrochemically pretreated glassy‐carbon enzyme electrodes

Wang¹,

González-Romero²

1993

Electroanalysis

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Substantial improvements in the performance of amperometric biosensors for alcohols are achieved by subjecting the glassy carbon transducer to an electrochemical pretreatment prior to the immobilization of alcohol dehydrogenase. The enzymatically generated dihydronicotinamide adenine dinucleotide (NADH) can thus be detected at a substantially (∼340 mV) lower potential compared to the untreated surface. Hence, highly sensitive low‐potential amperometric sensing of alcohols is accomplished without the assistance of a surface‐bound electron mediator. Applicability to alcoholic beverages is illustrated.

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“…The activation of carbon paste electrode using a high anodic potential is highly effective 5 . The appropriate initial potential was then selected and electrode allowed to stabilize for 30 s, a scan was then initiated from 0.2-1.2V using a scan rate of 100 mv/s.…”

Section: General Procedures For Calibration Curves -By Voltammetric Mmentioning

confidence: 99%

Electrochemical and Densitometric Determination of Zolmitriptan in Pharmaceutical Dosage Forms

Wassel

Bebawy

Ries

2007

Al-Azhar Bulletin of Science

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Two methods for the determination of antimigrain drug zolmitriptan in bulk powder and in pharmaceutical dosage forms by voltammetric and densitometric methods are developed.Voltammetric method depends on the oxidation of zolmitriptan on an activated carbon paste electrode. The compound is oxidized irreversibly at high positive potential. The response was evaluated with respect to pH; scan rate, nature of the buffer and other variables. The peak current at about 0.76V, with the maximum current at pH 5 ±0.2 acetate buffer. The mechanism of the reaction is controlled by oxidation of the N-H group in the indole ring. By differential pulse voltammetry, the calibration plot was linear in the range 3.99 x10 -7 -2.90The second method is based on the application of thin layer chromatographic separation of the studied drug in the presence of its degradation product followed by the densitometric measurements of the spot areas of the drug. After separation on silica gel GF254 plates using methanol: ammonia 25% (100:1.5 v/v) as mobile phase, the chromatographic zones corresponding to the spots of zolmitriptan were scanned at 285nm. The calibration function was established in the range of 1.00-9.00 µg/ spot. The suggested methods were used to determine the cited drug in bulk powder, and pharmaceutical dosage forms. Results were compared statistically with the reported method.

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Activation of glassy carbon electrodes by alternating current electrochemical treatment

Cited by 99 publications

References 17 publications

Electroanalysis of Norepinephrine at Bare Gold Electrode Pure and Modified with Gold Nanoparticles and S‐Functionalized Self‐Assembled Layers in Aqueous Solution. Part II

Electroanalysis of Norepinephrine at Bare Gold Electrode Pure and Modified with Gold Nanoparticles and S‐Functionalized Self‐Assembled Layers in Aqueous Solution. Part II

Amperometric biosensing of alcohols at electrochemically pretreated glassy‐carbon enzyme electrodes

Electrochemical and Densitometric Determination of Zolmitriptan in Pharmaceutical Dosage Forms

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