2018
DOI: 10.1080/23737867.2018.1468725
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Activation of the immune response by cytokines and its effect on tumour cells: a mathematical model

Abstract: In this paper, we present a mathematical model at the cellular level of the tumour-immune competition mediated by the cytokines. The model consists of a system of nonlinear differential equations describing the intracellular interactions between the tumour and the immune cells in the presence of the cytokines. A detailed phenomenological description of the model based on the kinetic theory for active particle approach is carried out to formulate the model. Well-posedness is presented to establish local and glo… Show more

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References 37 publications
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