“…3␣,5␣-THP also reduces ictal activity induced by perforant path-way stimulation (Frye, 1995) and that seen in seizureprone animals (Finn, Roberts, & Crabbe, 1995). The present finding that prenatally stressed females were less sensitive to exogenous 3␣,5␣-THP is consistent with these previous findings and others which show that females are particularly vulnerable to prenatal stress and variations in 3␣,5␣-THP (Almeida, Canoine, Ali, Holsboer, & Patchev, 1997;Devaud, Purdy, Finn, & Morrow, 1996;Devaud et al, 1995;Morrow, Devaud, Purdy, & Paul, 1995;Patchev, Hassan, Holsboer, & Almeida, 1996).…”