Over the past decade, the health domain has grown at a fast pace. The stakeholders are not only limited to patients, but also include formal and informal careers, doctors, research institutions and technological solution providers. As such, different technological ecosystems of interconnected health communities have arisen to adopt the best practices to improve the wellbeing and health of patients. In order to identify the lacks and opportunities in this area, this paper aims at providing a comprehensive overview of the ecosystems in the health domain, presenting a systematic mapping study of research projects developed in Europe and related to the field. The systematic mapping review was conducted on the AAL Programme, CORDIS and KEEP databases. The paper describes the methodology employed for conducting such a review, and provides an analysis of results that give an overview of the evolution of related European projects until today along with the conclusions obtained from the study. CCS CONCEPTS • Applied computing~Health care information systems • Software and its engineering • Software and its engineering → Ultralarge-scale systems • Software and its engineering → Designing software