The aim of this research is to develop a quantitative usability evaluation method (UEM) for elderly drivers, which has different weight values on each factor concerning physical and cognitive context of elderly drivers. An analysis of the relationship between universal design guidelines for elderly drivers and usability principles was conducted by using the quality function deployment method. In addition, developmental priorities are derived from analysis results of difficulty in achieving performance improvement, max relationship values, and relative weight. Furthermore, n and positive relationships among the universal design guidelines are defined by means of relationship analysis. Combining these results, a quantitative evaluation guideline for elderly drivers is derived, and based on the context and developmental goals of the developer, selective design is facilitated. The proposed UEM is compared with existing UEM in terms of thoroughness, validity, and effectiveness.