Active-oxygenating hollow Prussian blue nanosystems loaded with biomacromolecules for photodynamic/photothermal therapy of cancer and alleviating hypoxic tumors

2D Architectures-Transformed Conformational Nanoarchitectonics for Light-Augmented Nanocatalytic Chemodynamic and Photothermal/Photodynamic-Based Trimodal Therapies

“…Typically, in vivo photothermal imaging (PTI) studies are conducted to demonstrate photothermal efficacy due to no electromagnetic interference, excellent biosafety, reliability, and exceptional temperature sensitivity. In addition, these PTI findings can elucidate the intratumoral accumulation of the designed constructs toward exploring their targeting ability, in which accumulated photothermal conversion agents (PTCAs), including the concentration of drugs or PTCAs that can selectively absorb NIR radiation in different biological tissues. , This diagnostic tool utilizes infrared thermography to detect heat, convert it to an electronic signal, and calculate the resultant temperature in vivo . Specifically, the resultant images can validate the intratumoral accumulation of the nanoparticles that are internalized through the passively targeted formulations referred to as the EPR effect.…”