2011
DOI: 10.1200/jco.2010.32.8112
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Active Surveillance Program for Prostate Cancer: An Update of the Johns Hopkins Experience

Abstract: For carefully selected men, active surveillance with curative intent appears to be a safe alternative to immediate intervention. Limiting surveillance to very-low-risk patients may reduce the frequency of adverse outcomes.

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Cited by 542 publications
(509 citation statements)
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“…Most clinical studies mention T1c and T2a tumours almost exclusively. T1a/b cancer is either not included in the reports, not specified separately or represented only sparingly [20][21][22], e.g. 4.8% in the report by Klotz et al [8].…”
Section: Discussionmentioning
confidence: 99%
“…Most clinical studies mention T1c and T2a tumours almost exclusively. T1a/b cancer is either not included in the reports, not specified separately or represented only sparingly [20][21][22], e.g. 4.8% in the report by Klotz et al [8].…”
Section: Discussionmentioning
confidence: 99%
“…Criteria for AS set forth from published series are shown in Table 1 [7][8][9][10][11][12][13][14][15]. First described in 1994, and then updated in 2004, the Epstein criteria integrate biopsy criteria with clinical data to identify potentially low-risk tumors and are among the most commonly used methods to identify lowrisk disease [16,17].…”
Section: Criteria For Active Surveillancementioning
confidence: 99%
“…The cost of the Roth, Ramsey, Carlson 8-protein prostate cancer prognostic assay was provided by Metamark Genetics ($3,800). For patients on active surveillance, we calculated a bundled monthly cost based on the protocol recommended by Tosoian et al [18]. Specifically, the active surveillance protocol involved biannual office visits and PSA tests and one annual biopsy.…”
Section: Cost Inputsmentioning
confidence: 99%