Actividad Antibacteriana De Flavonoides Aislados Del Exudado Resinoso De Heliotropium Sinuatum: Efecto Del Tipo De Estructura

Modak, Brenda; Arrieta, Abel; Torres, René; Urzua, Y Alejandro

doi:10.4067/s0366-16442002000100005

Cited by 3 publications

(4 citation statements)

References 1 publication

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“…These effects and the structural requirements are not fully defined for the antimicrobial activity. There are studies that show there must be at least hydroxyl (-OH) and methoxy (-OCH 3 ) groups, and some degree of lipophilicity (Modak et al, 2002;Sánchez-Maldonado et al, 2011) as it is the case of phenolic compounds found in Moringa. These groups provoke an oxidative phosphorylation, causing a pH elevation; and therefore, toxicity.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

“…in Fodder for Feeding Japanese Quail (Coturnix coturnix japonica) al., 2002;Mukne et al, 2011). This effect is due to the high grade of hydrophobicity or lipid solubility, allowing with this, the separation of the lipidic structure of the membrane cell and mitochondria, messing its structure which causes its permeability, letting the migration of ions and another compounds to happen, resulting in an imbalance homeostatic (Rosas-Gallo & Lopez-Malo, 2011); and therefore, exercising a cytotoxic effect in the cells (García-García & Paulo-Garcia, 2008).…”

Section: Inclusion Of Moringa Leaf Powder (Moringa Oleifera)mentioning

confidence: 99%

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Inclusion of Moringa Leaf Powder (Moringa oleifera) in Fodder for Feeding Japanese Quail (Coturnix coturnix japonica)

Castillo

Portillo

León

et al. 2018

Rev. Bras. Cienc. Avic.

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Section: Antimicrobial Activitymentioning

confidence: 99%

Section: Inclusion Of Moringa Leaf Powder (Moringa Oleifera)mentioning

confidence: 99%

Inclusion of Moringa Leaf Powder (Moringa oleifera) in Fodder for Feeding Japanese Quail (Coturnix coturnix japonica)

Castillo

Portillo

León

et al. 2018

Rev. Bras. Cienc. Avic.

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“…We presumed that the effect observed may possibly be attributed to a combination of more than one biological and/or chemical interaction, since these resins and compounds possess multiple biological and chemical activities, such as antimicrobial and antioxidant [2][3][4][5][6]14].…”

mentioning

confidence: 99%

“…In search of an explanation of the role of this resin, it has been proposed that it can constitute the first stage of protection against predators. This protection can be due both to a mechanical effect, associated with the sticky character of the resin, which traps the predators, and to a chemical protection due to the presence of secondary metabolites that exhibit antimicrobial and antioxidant activities [2][3][4][5][6].…”

mentioning

confidence: 99%

Effect on Hantavirus Replication of Resins from Heliotropium Species and Other Selected Compounds

Gaona

Araya

Canobra

2008

Natural Product Communications

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The present investigation on Heliotropium species was carried out in an attempt to detect possible replication inhibitors of Hantavirus variety Andes. Using the plaque inhibition assay, we have evaluated a group of compounds and resins isolated from Heliotropium species. The antiviral activity was determined between the concentration range 2.5-40.0 µg/mL. Antiviral activity was detected in all the tested resins, particularly that of H. huascoense, with an EC 50 value of 12.5 μg/mL. Of the pure compounds tested, the aromatic geranyl derivative filifolinone was the most active. The EC 50 value of this compound, 11.3 μg/mL, was similar to that of the control, ribavirin. However, these substances were not selective, but this screening has served to identify those compounds with most promise.

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Biophenolic compounds and metal ions associated with the antioxidant and antibacterial activity of the ethanolic extract of Heliotropium arborescens L. leaves from the Andean region of Ayacucho-Peru

Alvarado,

Chávez,

García

et al. 2024

PHAR

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Heliotropium arborescens (Galán de Mera et al. 2022) is a herbaceous plant that contains various biophenolic compounds that exhibit antibacterial property and antioxidant activity that could prevent diseases caused by free radicals. The objective was to study the biophenolic compounds and metal ions associated with the in vitro antioxidant and antibacterial activity of the ethanolic extract of Heliotropium arborescens L. leaves from the Andean region of Ayacucho-Peru. The total polyphenolic content (TPC) was determined by the Folin-Ciocalteu method; Total flavonoid content (TFC) was determined by spectrophotometry at 510 nm, TFC was expressed in mg quercetin/g sample (mg QE/g). Antioxidant activity by three in vitro methods; determination of metals by flame atomic absorption spectrophotometry (FAAS) and antibacterial activity by agar diffusion method. The values obtained from the TPC were 306.80±0.05 mg GAE/g, TFC 111.53±0.25 mg QE/g. Antioxidant activity: DPPH IC50 37.55±0.04 µL and 65.64±0.10 µL, at 0.47 and 0.93 mg/mL extract, respectively; ABTS 0.20±0.01 mM TEAC/g (0.41 mg/mL extract) and 0.47±0.01 (0.82 mg/mL extract); FRAP 0.24±0.01 mM TEAC/g (0.94 mg/mL extract) and 0.46±0.02 mM TEAC/g (1.88 mg/mL extract). Correlation relationship TFC/DPPH (r=0.9994; R2 0.9989), TFC/ABTS (r = 0.9572; R2 0.9998) and TFC/FRAP (r = 09933; R2 0.9868). Calcium 1.22±0.04, copper 0.77±0.05, magnesium 851.7±3.06 and zinc 20.63±1.19 mg/100 g were found in all cases. Antibacterial activity on Bacillus subtilis (ATCC 6633) and Staphylococcus aureus (ATCC 25923) with a minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) > 400 μg/mL. It is concluded that the total biophenolic components and metals of the ethanolic extract of the leaves of H. arborescens L. show potential antioxidant activity, and moderate antibacterial activity against Bacillus subtilis and Staphylococcus aureus. Graphical abstract:

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Actividad Antibacteriana De Flavonoides Aislados Del Exudado Resinoso De Heliotropium Sinuatum: Efecto Del Tipo De Estructura

Cited by 3 publications

References 1 publication

Inclusion of Moringa Leaf Powder (Moringa oleifera) in Fodder for Feeding Japanese Quail (Coturnix coturnix japonica)

Inclusion of Moringa Leaf Powder (Moringa oleifera) in Fodder for Feeding Japanese Quail (Coturnix coturnix japonica)

Effect on Hantavirus Replication of Resins from Heliotropium Species and Other Selected Compounds

Biophenolic compounds and metal ions associated with the antioxidant and antibacterial activity of the ethanolic extract of Heliotropium arborescens L. leaves from the Andean region of Ayacucho-Peru

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