Actividad antibacteriana in vitro de propóleos chilenos sobre Helicobacter pylori

Villanueva, María Paz; González, Mercedes Hernández; Fernández, Heriberto; Wilson, Myra; Manquián, Nimia; Otth, Carola; Otth, L

doi:10.4067/s0716-10182015000600007

Cited by 7 publications

(1 citation statement)

References 13 publications

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“…Other studies have evaluated in vitro the inhibitory activity of 22 propolis extracts from different Chilean regions on 10 strains of Helicobacter pylori isolated from gastric mucosa in vitro. The results show that Chilean propolis has an effective anti- Helicobacter pylori activity [31, 32]. …”

Section: Discussionmentioning

confidence: 99%

The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial

Mujica

Orrego

Pérez

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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Although there is evidence of the benefits of propolis on human health, the vast majority of studies have been conducted using animal models. The present study includes the chemical characterization and clinical evaluation of the effects of the oral administration of propolis solution on the oxidative status and modulation of lipids in a human population in Talca, Chile. Chemical characterization of propolis, total phenol, flavonoids, and total antioxidant capacity were determined by ORAC. Identification of phenols and flavonoids in propolis was assessed by HPLC-DAD. A double-blind, placebo-controlled clinical trial was conducted. Subjects provided informed consent form and the Bioethics Committee of the Universidad de Talca approved protocol. Eligible subjects (n = 67) were randomized in two groups: propolis (n = 35) and placebo (n = 32). All subjects were evaluated at 0 (baseline), 45, and 90 days. In the propolis group, we observed that increases in HDL-c went from 53.9 ± 11.9 to 65.8 ± 16.7 mg/dL (p < 0.001) from baseline to 90 days. Compared to placebo subjects, consumption of propolis induced a net increase in GSH levels (p < 0.0001) and a decrease (p < 0.001) in TBARS levels for the propolis group. Our findings indicate potential benefits of propolis use in human health. The use of propolis appears to have positive effects on oxidative status and improvement of HDL-c, both of which contribute to a reduced risk of cardiovascular disease.

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Section: Discussionmentioning

confidence: 99%

The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial

Mujica

Orrego

Pérez

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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Propolis polyphenolic compounds affect the viability and structure of Helicobacter pylori in vitro

Romero

Freire

Pastene

et al. 2019

Revista Brasileira de Farmacognosia

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Propolis and Its Potential to Treat Gastrointestinal Disorders

Silva

Souza

Jaouni

et al. 2018

Evidence-Based Complementary and Alternative Medicine

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There are a number of disorders that affect the gastrointestinal tract. Such disorders have become a global emerging disease with a high incidence and prevalence rates worldwide. Inflammatory and ulcerative processes of the stomach or intestines, such as gastritis, ulcers, colitis, and mucositis, afflict a significant proportion of people throughout the world. The role of herbal-derived medicines has been extensively explored in order to develop new effective and safe strategies to improve the available gastrointestinal therapies that are currently used in the clinical practice. Studies on the efficacy of propolis (a unique resinous aromatic substance produced by honeybees from different types of species of plants) are promising and propolis has been effective in the treatment of several pathological conditions. This review, therefore, summarizes and critiques the contents of some relevant published scientific papers (including those related to clinical trials) in order to demonstrate the therapeutic value of propolis and its active compounds in the treatment and prevention of gastrointestinal diseases.

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Actividad antibacteriana in vitro de propóleos chilenos sobre Helicobacter pylori

Cited by 7 publications

References 13 publications

The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial

The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial

Propolis polyphenolic compounds affect the viability and structure of Helicobacter pylori in vitro

Propolis and Its Potential to Treat Gastrointestinal Disorders

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