Activities of aminotransferases after treatment with streptokinase for acute myocardial infarction.

Abstract

been reported cytologically as non-neoplastic the cytological specimens were reviewed. In one case from the first year of the study a retrospective cytological diagnosis of papillary carcinoma was made, but in all other cases there were no cytological features suggesting neoplasia, although in two cases the specimens would now be classed as unsatisfactory.Aspiration cytology is an adjunct to the management of thyroid swellings but is not a definitive diagnostic test and, in particular, negative results do not exclude neoplastic disease. Definition of an optimum management policy depends on further study, which should include the financial and psychological implications of repeated clinic attendances and of repeated aspiration, which may culminate in delayed surgical treatment.

Adverse reaction to streptokinase with multiple systemic manifestations

“…Sallen et al [14] and Freimark et al [15] reported a cytolytic hepatic pattern without changes in bilirubin blood levels, whereas our patient had high blood levels of total and direct bilirubin. Maclennan et aL [3] similarly described that treatment of acute myocardial infarction with streptokinase could lead to a rise in the levels of alanine aminotransferase, aspartate aminotransferase, bilirubin and gammaglutamyl transferase.…”

“…In fact, they have been shown to be mediated by circulating immunoglobulins [2]. Other secondary effects of this agent are hyperthermia, hypotension, elevated levels of hepatic enzymes [3] and haemorrhagic complications.…”