Activities of total, cytoplasmic, and mitochondrial superoxide dismutase enzymes in sera and pleural fluids from patients with lung cancer

Durak, İlker; Canbolat, Orhan; Kavutçu, Mustafa; Öztürk, Hasan Serdar; Yurtarslani, Zühal

doi:10.1002/(sici)1098-2825(1996)10:1<17::aid-jcla4>3.0.co;2-i

Cited by 142 publications

(65 citation statements)

References 13 publications

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“…Malondialdehyde levels were measured by the thiobarbituric acid reactive substances (TBARS) method [12] . Superoxide dismutase activity was measured as described [13] . In this method, one unit for SOD activity was expressed as the enzyme protein amount causing 50 % inhibition in nitroblue tetrazolium (NBT) reduction rate.…”

Section: Methodsmentioning

confidence: 99%

Effects of Computer Use on Human Salivary Oxidant/Antioxidant Status

Ergüder¹,

Durak²

2006

OnLine J. of Biological Sciences

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Abstract:Computers are widely used in recent years but their effects on human health completely are known. The aim of this study was to investigate possible effects of computer use on human salivary oxidant / antioxidant system. Ten subjects were included in the study. Three saliva samples were taken from the subjects. First was obtained before computer use, second and third samples were obtained two and four hours after they started computer use. Malondialdehyde (MDA) levels and superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and adenosine deaminase (ADA) enzyme activities were measured in each saliva sample. Malondialdehyde (MDA) level (mean ± standard deviation) was found to increase in the saliva samples obtained after computer use. SOD and ADA activities decreased but, CAT activity increased during this period. Our results show that computer-released radiation causes changes in enzymatic antioxidant defense system and, leads to oxidant stress in saliva samples from subjects. It has been suggested that subjects who use computer intensively should be consumed more antioxidant foods in order to prevent probable oxidation reactions in their bodies.

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Section: Methodsmentioning

confidence: 99%

Effects of Computer Use on Human Salivary Oxidant/Antioxidant Status

Ergüder¹,

Durak²

2006

OnLine J. of Biological Sciences

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“…Similarly, Durak et al determined higher serum and pleural fluid SOD enzyme activities in patients with lung cancer than in those of healthy controls (27).…”

Section: Discussionmentioning

confidence: 95%

The Role of Superoxide Dismutase (SOD) Activity And Malondialdehyde (MDA) Levels in The Differentiation of Benign-Malign Pleural Effusion

Çiftçi¹,

Güney²,

Bilgehan³

et al. 2004

Ankara Sa

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“…SOD, CAT and GST enzyme analyses were done as described by Durak, Aebi and Habig et al respectively (12)(13)(14). The SOD activity method is based on the measurement of absorbance increase at 560 nm due to reduction of NBT to NBTH2.…”

Section: Biochemical Evaluationmentioning

confidence: 99%

The Effect of Dexmedetomidine on Ischemia Reperfusion Injury in Myocard of Rat

Özer¹,

Erer²,

Oktar³

et al. 2018

GMJ

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Objective: The aim of this study was to evaluate the effect of dexmedetomidine (100µg/kg-ip) on ischemia reperfusion (IR) injury in myocard of rats. Methods: Twenty-four Wistar Albino rats were separated into four groups. There were four experimental groups (Group C (Control; n=6), Group IR (ischemia-reperfusion, n=6), Group D (Dexmedetomidine; n=6), underwent left thoracotomy and received ip dexmedetomidine without ischemia and reperfusion and Group IR-D (IR-Dexmedetomidine; n=6) was administrated 100µg/kg dexmedetomidine via ip route 30 minutes before ligating the left coronary artery. A small plastic snare was threaded through the ligature and placed in contact with the heart. To produce IR, a branch of the left coronary artery was occluded for 30 min followed by two hours of reperfusion. However, after the above procedure, the coronary artery was not occluded or reperfused in the control rats. At the end of the study, myocard tissue was obtained for biochemical, histochemical and immunohistochemical determination/ analyses . Results: Myonecrosis, cell infiltration and edema were significantly higher in the IR group than in the C and D groups. In the IR-D group, myonecrosis, cell infiltration and edema were significantly lower than in the IR group.TBARS levels were found to be significantly higher in the IR group than in the C and D groups.TBARSlevels in the IR-D group were found to be significantly lower than in the IR group.SOD enzyme activity was found to be significantly lower in the IR group than in the C group. In the IR-D group, SOD enzyme activity was found to be significantly higherthan the IR group. Conclusion: Dexmedetomidine removed degenerative effects after ischemia reperfusion in ischemia reperfusion group and we may conclude that dexmedetomidine may have regenerative effects on IR injury .

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Activities of total, cytoplasmic, and mitochondrial superoxide dismutase enzymes in sera and pleural fluids from patients with lung cancer

Cited by 142 publications

References 13 publications

Effects of Computer Use on Human Salivary Oxidant/Antioxidant Status

Effects of Computer Use on Human Salivary Oxidant/Antioxidant Status

The Role of Superoxide Dismutase (SOD) Activity And Malondialdehyde (MDA) Levels in The Differentiation of Benign-Malign Pleural Effusion

The Effect of Dexmedetomidine on Ischemia Reperfusion Injury in Myocard of Rat

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