Activity of Intracellular Metabolism at Neutrophils in Patients with Metabolic Syndrome

Kratnov, Andrey Eu.

doi:10.5171/2014.963868

Cited by 1 publication

(1 citation statement)

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“…The source of active forms of oxygen at obesity belonging to the basic modifiable risk factors of cardiovascular diseases can be the neutrophils. In patients with III degree of obesity, the increase of formation of oxygen radicals of neutrophils is accompanied by the decrease in activity intracellular antioxidative protection that can promote development of oxidative stress [4]. The INTERHEART case-control study, which had the benefit of a very large sample size, in addition to the risk factors of cardiovascular diseases also revealed antirisk factors-sufficient use of vegetables and fruits, regular reception of small doses of alcohol, and regular physical activity [5].…”

Section: Introductionmentioning

confidence: 99%

Influence of Antirisk Factors of Cardiovascular Diseases on Intracellular Metabolism of Neutrophils in Men with Obesity

Kratnov¹,

Timganova²

2015

WJCS

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Background: The factor promoting development of oxidative stress at obesity can be the neutrophils. Objective: To study the influence antirisk factors of cardiovascular diseases on intracellular metabolism of neutrophils in men with peripheral obesity. Methods: In 103 male patients aged 23 to 64 years without coronary heart disease, we studied the presence obesity, antirisk factors of cardiovascular diseases, and the metabolic activity of neutrophils. Results: It is identified that obesity in men associates with more rare use of crude vegetables or fruits every day, and also low physical activity. The daily uses of crude vegetables or fruits, and also the increase of physical activity in obese men promote increase intracellular activity of antioxidative protection at neutrophils. Conclusion: The antirisk factors of cardiovascular diseases increase activity antioxidative protection of neutrophils in men with peripheral obesity, reducing the probability of development of oxidative stress.

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Section: Introductionmentioning

confidence: 99%