1948
DOI: 10.1126/science.107.2781.397
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Activity of Vitamin B 12 for the Growth of Lactobacillus lactis

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Cited by 124 publications
(50 citation statements)
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“…The bacteriostatic power of the two ointments has been determined by the F. D. A. agar cup-plate method. dicated more than 50% decomposition of the vitamin BIZ after storage at 28' to 30' for twenty-four hours, as determined by the cup-plate assay procedure (I), utilizing Lactobacillus Zactis Dorner (2) as the test organism. The assays of control solutions containing no ascorbic acid indicated no vitamin Bn decomposition.…”
Section: Discussionmentioning
confidence: 99%
“…The bacteriostatic power of the two ointments has been determined by the F. D. A. agar cup-plate method. dicated more than 50% decomposition of the vitamin BIZ after storage at 28' to 30' for twenty-four hours, as determined by the cup-plate assay procedure (I), utilizing Lactobacillus Zactis Dorner (2) as the test organism. The assays of control solutions containing no ascorbic acid indicated no vitamin Bn decomposition.…”
Section: Discussionmentioning
confidence: 99%
“…Indeed, considering it in retrospect, the vitamin B12 isolation by the American group of researchers at Merck in comparison to the English group at Glaxo was due to the possibility of the former one to make use, instead of clinical tests, of the microbiological method. This was based on the growth response of Lactobacillus lactis (Dorner strain) to the vitamin as first described by Shorb (1947Shorb ( , 1948.…”
Section: Bioassay Methodsmentioning
confidence: 99%
“…The vitamin B12 produced was measured by the microbiological assay based on the growth response of Lactobacillus lactis (Domer strain) devised by Shorb (1947Shorb ( , 1948.…”
Section: Introductionmentioning
confidence: 99%
“…tberrnoaceticurn (Gleason and Hogenkamp, 1972). Genus Lactobacillus: L. leicbmannii (Gleason and Hogenkamp, 1972;Abeles and Beck, 1962;Hoffmann et al, 1948;Skeggs et al, 1948), L. lactis (Abeles and Beck, 1967;Shorb, 1948), L. acidopbilus, L. delbrueckii, and L. belveticus (Abeles and Beck, 1967;Kitay et al, 1950). Other bacteria: P. sberrnanii (Shemin, 1968), C. nepbridii (Gleason and Hogenkamp, 1972;Bergey's Manual, 1974), C. carotenogenurn (Pradhan and Bhat, 1962), Flavobacteriurn (Lascelles andCross, 1955), Cb.…”
Section: A Biological Distributionmentioning
confidence: 94%