Actualización en el tratamiento farmacológico del dolor neuropático

Nerve Injury and Photobiomodulation, a Promising Opportunity: A Scoping Review on Laser Assisted Protocols for Lesions in the Oral Region

“…A wide array of therapeutic approaches are employed to mitigate pain, showcasing the versatility of medical interventions in addressing this complex issue. These methods encompass the utilization of painkillers, which encompass both non-opioid analgesics and anti-inflammatory medications, offering rapid relief by targeting pain pathways and reducing inflammation [72][73][74][75][76][77]. Additionally, corticosteroids find application due to their potent anti-inflammatory properties, effectively alleviating pain associated with inflammatory conditions.…”

“…Drugs such as tricyclic antidepressants, anticonvulsants, and serotonin-norepinephrine reuptake inhibitors (SNRIs) are commonly prescribed. These medications target specific pathways involved in nerve transmission and modulation, helping to alleviate the distinctive burning, shooting, or tingling sensations associated with neuropathic pain [72][73][74][75][76][77]. While painkillers offer relief, their effectiveness varies among individuals, and a multidisciplinary approach may be needed for comprehensive neuropathic pain management.…”

“…Similarly, muscle relaxants are employed to ease pain stemming from muscle tension or spasms, allowing for enhanced comfort and improved mobility. Nerve denervation or ablation is considered in cases of severe neuropathic pain that is unresponsive to conservative treatments [72][73][74][75][76][77]. This procedure involves deliberately disrupting the nerve pathways responsible for transmitting pain signals, often providing relief when other methods have failed.…”

“…Post-denervation rehabilitation, including physical therapy, is crucial to optimize outcomes. The close collaboration between the patient, pain specialist, and interdisciplinary team is vital to making informed decisions regarding nerve denervation as a therapeutic option for refractory neuropathic pain [72][73][74][75][76][77]. Physical therapy is a cornerstone in pain management, focusing on rehabilitation, strengthening, and restoring functional capacity.…”

“…This approach not only addresses the root causes of pain but also empowers patients with long-term coping mechanisms and an improved overall well-being. An intriguing avenue lies in the administration of parietal hyaluronic acid preparations or biological substances, such as stem cells [72][73][74][75][76][77]. These innovative therapies target tissue regeneration and repair, holding the potential for more sustainable pain relief by addressing underlying structural issues.…”