Acupuncture for treating overactive bladder in adults

Hargreaves, Emma; Baker, Katherine; Barry, Gill; Harding, Christopher; Zhang, Yingying; Kandala, Ngianga‐Bakwin; Zhang, Xiaowen; Kernohan, Ashleigh; Clarkson, C.

doi:10.1002/14651858.cd013519.pub2

Cited by 9 publications

(4 citation statements)

References 82 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…And EA stimulation at BL32 and BL33 can activate S2 and S3 afferent nerve fibers deep in BL32 and BL33 to promote detrusor smooth muscle contractions ( 17 ). The therapeutic effects and high safety of EA have been verified in patients suffering from certain lower urinary tract diseases including stress urinary incontinence and overactive bladder ( 18 , 19 ). However, few studies have examined the effect of EA on CUR secondary to pelvic or lumbosacral tumor resection surgeries.…”

Section: Introductionmentioning

confidence: 99%

Effects of electroacupuncture on chronic urinary retention after pelvic or lumbosacral tumor resection surgeries: a retrospective cohort study

Yang,

Zhu,

Yao

et al. 2024

Transl Androl Urol

View full text Add to dashboard Cite

Background Chronic urinary retention (CUR) resulting from lower motor neuron lesions (LMNL) is a medical condition secondary to pelvic or lumbosacral tumor resection surgeries. Electroacupuncture (EA) is proved to be effective and safe in treating certain lower urinary tract disorders. However, the clinical benefit and optimal duration of EA treatment for CUR following LMNL remain unknown. Methods Using a retrospective cohort design, 20 eligible patients diagnosed with CUR resulting from LMNL secondary to pelvic or lumbosacral tumor resection surgeries were included from March 1, 2017, to June 30, 2020. The patients were treated by EA three times a week for 2 to 12 weeks and followed up for 24 weeks after treatment. The electric stimulators with a 5-Hz continuous wave (5–10 mA intensity) were separately connected to bilateral Ciliao (BL32), bilateral Zhongliao (BL33), and bilateral Huiyang (BL35), and stimulators with a 10-Hz continuous wave (1–2 mA intensity) were connected to bilateral Sanyinjiao (SP6). Current intensity was adjusted according to the patients’ individual tolerance. The median follow-up was 32 weeks (range, 26–36 weeks). Responders were defined as patients whose post-void residuals (PVR) reduced by 50% or more from baseline. Adverse event was recorded. Results Totally 20 patients [mean (standard deviation) age, 48.1 (15.5) years; 9 men (45.0%); 11 women (55.0%)] were included. Of the 20 patients, 14 (70.0%) had responded to EA treatment and stopped catheterization for achieving satisfactory spontaneous urination (PVR <100 mL without complications), 7 (35.0%) had complete resolution (90–100% reduction in PVR from baseline), and 13 (65.0%) scored 1 (much better) or 2 (moderately better) in the Patient Global Impression of Improvement (PGI-I) assessment. Moreover, 6 (30.0%) patients had responded within 4 weeks of EA treatment. According to Kaplan-Meier survival curve, we found that more than 50% patients could respond to EA treatment within 8 weeks or longer. None of the responders had ever experienced relapse in 24 weeks after EA treatment ended. None of the patients manifested urinary tract infection (UTI), newly diagnosed hydroureter or hydronephrosis. One patient diagnosed with hydronephrosis at baseline recovered after 12-week EA treatment. Two patients with UTI at baseline were prescribed antibiotics and did not present UTI again during the follow-up. Conclusions EA could be a promising treatment option for CUR caused by LMNL following pelvic or lumbosacral tumor resection surgeries, with long-term effects and a good safety profile. The optimal duration of EA should be of 8 weeks at least. But this was a retrospective cohort study of a small sample size, so future studies are needed to investigate EA in larger populations in randomized controlled trials.

show abstract

Section: Introductionmentioning

confidence: 99%

Effects of electroacupuncture on chronic urinary retention after pelvic or lumbosacral tumor resection surgeries: a retrospective cohort study

Yang,

Zhu,

Yao

et al. 2024

Transl Androl Urol

View full text Add to dashboard Cite

show abstract

“…With the advancement of science and technology, more studies have increasingly explored and confirmed the efficacy of acupuncture [ 9 ]. Some Cochrane evidence suggests the positive effects of acupuncture in the treatment of certain diseases and symptoms, such as overactive bladder [ 10 ], chronic nonspecific low back pain [ 11 ], and polycystic ovarian syndrome [ 12 ]. The popularity of acupuncture therapy and the patient’s need for integrative medicine and personalized treatment have prompted the broader practice of acupuncture in Western countries [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Therapeutic effects of acupuncture therapy for kidney function and common symptoms in patients with chronic kidney disease: a systematic review and meta-analysis

Liu,

Zhang,

Bai

et al. 2024

Renal Failure

View full text Add to dashboard Cite

Purpose: The number of clinical reports of acupuncture therapy in chronic kidney disease (CKD) is gradually increasing. This systematic review and meta-analysis aim to examine the therapeutic role of acupuncture therapy in kidney function and common symptoms in CKD patients. Methods: We searched Embase, PubMed, Scopus, Web of Science, China National Knowledge Infrastructure, WanFang, and WeiPu for randomized controlled trials comparing acupuncture treatment with control or placebo groups. We assessed the effect of acupuncture therapy in CKD patients using a meta-analysis with the hartung-knapp-sidik-jonkman random effects model. In addition, we visualized keyword co-occurrence overlay visualization with the help of VOSviewer software to describe the research hotspots of acupuncture therapy and CKD. Results: A total of 24 studies involving 1494 participants were included. Compared to the control group, acupuncture therapy reduced serum creatinine levels (standardized mean difference [SMD]: −0.57; 95% CI −1.05 to −0.09) and relieved pruritus (SMD: −2.20; 95% CI −3.84, −0.57) in patients with CKD, while the TSA showed that the included sample size did not exceed the required information size. The included studies did not report acupuncture-related adverse events. Conclusions: Acupuncture is an effective and safe treatment for improving kidney function and relieving pruritic symptoms in patients with CKD, but the very low evidence may limit this conclusion. The TSA suggests that high-quality trials are needed to validate the efficacy of acupuncture therapy.

show abstract

“…Electroacupuncture (EA) refers to the practice of inserting multiple fine needles with the addition of electrical stimulation at acupoints, which have specific effects on symptoms, according to Traditional Chinese Medicine (TCM) theory (19). The efficacy and safety of EA have been testified in adult patients with urinary disorders, such as urinary incontinence, overactive bladder, and urinary retention (20)(21)(22)(23)(24). By needling within the skin and muscles that supplied by the nerves from the pelvic, pudendal and hypogastric nerve roots, which are directly related to the lower urinary tract, EA may influence bladder function through signaling changes from nervous system to the bladder (25)(26)(27).…”

Section: Introductionmentioning

confidence: 99%

Effects of electroacupuncture on pediatric chronic urinary retention: a case-series study

Gao

Yao

et al. 2023

Front. Pediatr.

View full text Add to dashboard Cite

ObjectivesThis study aims to preliminarily evaluate the effect and safety of electroacupuncture (EA) in treating pediatric chronic urinary retention (CUR) following lumbosacral surgeries, with treatment duration evaluated.MethodsThis prospective case-series study was performed from August 5, 2017, to July 31, 2022. Pediatric patients diagnosed with CUR following lumbosacral surgeries were included and treated by EA for 2–16 weeks. Responders were defined as participants achieving a reduction of 50% or more in post void residuals (PVR) from baseline. Time-to-event analysis was applied to explore the association between EA treatment duration and response rate. Adverse event was recorded.ResultsTotally 14 participants (mean [SD] age, 12 [4] years) completed EA treatment. Response rate was 71% (10/14) at the 12th week. 50% (7/14) of participants removed catheters at the 12th week, and none of them experienced re-catheterization in the 24-week follow-up. No serious adverse event was reported. Time-to-event analysis estimated that over 50% patients could respond to EA of more than 8 weeks. Subgroup analysis showed that participants with baseline PVR ≥300 ml and CUR duration ≥12 months experienced longer EA duration to reach the response rate of 50%, compared with those whose PVR <300 ml and CUR duration <12 months (median value: 12 weeks vs. 8 weeks, 12 weeks vs. 4 weeks, respectively).ConclusionsEA could reduce PVR for pediatric patients suffering from CUR following lumbosacral surgeries, with long-term efficacy and safety. EA treatment of more than 8 weeks was reasonable. Further study of a larger sample and controlling is needed.Clinical Trial Registrationwww.chictr.org.cn, identifier, ChiCTR1800020222.

show abstract

Acupuncture for treating overactive bladder in adults

Abstract: This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:To assess the e ects of acupuncture for treating OAB in adults; and summarise the principal findings of relevant economic evaluations.

Cited by 9 publications

References 82 publications

Effects of electroacupuncture on chronic urinary retention after pelvic or lumbosacral tumor resection surgeries: a retrospective cohort study

Effects of electroacupuncture on chronic urinary retention after pelvic or lumbosacral tumor resection surgeries: a retrospective cohort study

Therapeutic effects of acupuncture therapy for kidney function and common symptoms in patients with chronic kidney disease: a systematic review and meta-analysis

Effects of electroacupuncture on pediatric chronic urinary retention: a case-series study

Contact Info

Product

Resources

About