Acupuncture prevents 6-hydroxydopamine-induced neuronal death in the nigrostriatal dopaminergic system in the rat Parkinson’s disease model

Park, Hi-Joon; Lim, Sabina; Joo, Wan Seok; Yin, Chang Shik; Lee, Hyangsook; Lee, Hye Jung; Seo, Jung Chul; Leem, Kang‐Hyun; Son, Yang; Kim, Youn Jung; Kim, Sang Hoon; Kim, Yong Sik; Chung, Joo Ho

doi:10.1016/s0014-4886(02)00031-6

Cited by 115 publications

(84 citation statements)

References 16 publications

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“…Park et al 30) and Kang et al 31) reported that AT prevented 6-hydroxydopamine-induced neuronal death and inhibited microglial activation in PD animal models. Bee venom AT was also associated with neuroprotection 32,33) .…”

Section: Evaluation Methodsmentioning

confidence: 99%

Current Status of Intervention Studies on Acupuncture for Parkinson’s Disease

2017

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Section: Evaluation Methodsmentioning

confidence: 99%

Current Status of Intervention Studies on Acupuncture for Parkinson’s Disease

2017

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“…This acupoint, which is on the fibular aspect of the leg, in the depression anterior and distal to the head of the fibula, was chosen because it is reported that it leads to significant neuroprotective effects in PD animal models [6,46] and significant improvements in patients with PD [34,47]. For verum acupuncture stimulation (ACUP), the needle (0.25 × 40 mm, Dong Bang Acupuncture Inc. Seoul, Korea) was manually inserted into the right GB 34 to a depth of approximately 1.0 cm.…”

Section: Acupuncturementioning

confidence: 99%

A Case Report of Drug-Induced Parkinsonism Treated with Jodeung-san and Electro-acupuncture at GB34

Kim¹,

Song²,

Kim³

et al. 2017

J Int Korean Med

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Background: Acupuncture is increasingly used as an additional treatment for patients with Parkinson's disease (PD). Methods: In this functional magnetic resonance imaging study, brain activation in response to acupuncture in a group of 12 patients with PD was compared with a group of 12 healthy participants. Acupuncture was conducted on a specific acupoint, the right GB 34 (Yanglingquan), which is a frequently used acupoint for motor function treatment in the oriental medical field.Results: Acupuncture stimulation on this acupoint activates the prefrontal cortex, precentral gyrus, and putamen in patients with PD; areas that are known to be impaired in patients with PD. Compared with healthy participants, patients with PD showed significantly higher brain activity in the prefrontal cortex and precentral gyrus, especially visible in the left hemisphere. Conclusions:The neuroimaging results of our study suggest that in future acupuncture research; the prefrontal cortex as well as the precentral gyrus should be treated for symptoms of Parkinson's disease and that GB 34 seems to be a suitable acupoint. Moreover, acupuncture evoked different brain activations in patients with Parkinson's disease than in healthy participants in our study, stressing the importance of conducting acupuncture studies on both healthy participants as well as patients within the same study, in order to detect acupuncture efficacy.Trial registration: KCT0001122 at cris.nih.go.kr (registration date: 20140530)

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“…Kim et al, 2005; H.J. Park et al, 2003;Y.P. Yu et al, 2010) and medial forebrain bundle transection (Jia et al, 2009(Jia et al, , 2010X.B.…”

Section: 'Gdnf-acupuncture'?mentioning

confidence: 99%