Acupuncture Treatment for Hypertension: A Case Study

Zhang, Lili; Peng-fei, Shen; Wang, Shu

doi:10.1136/acupmed-2013-010407

Cited by 12 publications

(9 citation statements)

References 7 publications

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“…Acupoints used here are bilateral Renying (ST9), Hegu (LI4), Quchi (LI11), Taichong (LR3), and Zusanli (ST36). The acupoint locations with reference to the World Health Organization (WHO) standards in the Western Pacific Region, and the corresponding manipulations of the aforementioned acupoints are listed in Table 3 , which accord with those described in a previous paper [ 32 ]. All the manipulations will be applied for 1 min and the needles are retained for 30 min.…”

Section: Methodssupporting

confidence: 75%

Acupuncture lowering blood pressure for secondary prevention of stroke: a study protocol for a multicenter randomized controlled trial

Gao

Wang

et al. 2017

Trials

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BackgroundStroke is the prime cause of morbidity and mortality in the general population, and hypertension will increase the recurrence and mortality of stroke. We report a protocol of a pragmatic randomized controlled trial (RCT) using blood pressure (BP)-lowering acupuncture add-on treatment to treat patients with hypertension and stroke.MethodsThis is a large-scale, multicenter, subject-, assessor- and analyst-blinded, pragmatic RCT. A total of 480 patients with hypertension and ischemic stroke will be randomly assigned to two groups: an experimental group and a control group. The experimental group will receive “HuoXueSanFeng” acupuncture combined with one antihypertensive medication in addition to routine ischemic stroke treatment. The control group will only receive one antihypertensive medication and basic treatments for ischemic stroke. HuoXueSanFeng acupuncture will be given for six sessions weekly for the first 6 weeks and three times weekly for the next 6 weeks. A 9-month follow-up will, thereafter, be conducted. Antihypertensive medication will be adjusted based on BP levels. The primary outcome will be the recurrence of stroke. The secondary outcomes including 24-h ambulatory BP, the TCM syndrome score, the Short Form 36-item Health Survey (SF-36), the National Institute of Health Stroke Scale (NIHSS), as well as the Barthel Index (BI) scale will be assessed at baseline, 6 weeks and 12 weeks post initiating treatments; cardiac ultrasound, carotid artery ultrasound, transcranial Doppler, and lower extremity ultrasound will be evaluated at baseline and 12 weeks after treatment. The safety of acupuncture will also be assessed.DiscussionWe aim to determine the clinical effects of controlling BP for secondary prevention of stroke with acupuncture add-on treatment.Trial registrationClinicalTrials.gov, ID: NCT02967484. Registered on 13 February 2017; last updated on 27 June 2017.Electronic supplementary materialThe online version of this article (doi:10.1186/s13063-017-2171-5) contains supplementary material, which is available to authorized users.

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Section: Methodssupporting

confidence: 75%

Acupuncture lowering blood pressure for secondary prevention of stroke: a study protocol for a multicenter randomized controlled trial

Gao

Wang

et al. 2017

Trials

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“…Objectively speaking, acupuncture can be used as an adjunct to antihypertensive drugs for a larger reduction of high BP [11] in patients with both hypertension and stroke, particularly when they experience the side effects of drugs [12,13]; this aspect of acupuncture for the treatment of hypertension can support the judgment of the above-mentioned meta-analysis by Katsanos et al [7]. On the other hand, the meta-analysis by Wang et al [6] indicates that multiple targets other than regulation of the BP are needed for preventing stroke recurrence.…”

Section: Introductionmentioning

confidence: 99%

Regulation of Hypertension for Secondary Prevention of Stroke: The Possible ‘Bridging Function' of Acupuncture

Zheng¹,

Han²,

Du³

et al. 2018

Complement Med Res

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Worldwide, stroke is the leading cause of mortality and disability, with hypertension being an independent risk factor for a secondary stroke. Acupuncture for the treatment of hypertension gains more attention in alternative and complementary medicine, but the results are inconsistent. Few studies regarding the secondary prevention of stroke by managing hypertension with acupuncture have been carried out as there are some problems regarding the antihypertensive drug status in the secondary prevention of stroke. Still, the potential of acupuncture in regulating the blood pressure for secondary stroke prevention deserves our focus. This review is based on papers recorded in the PubMed, Embase, and Web of Science databases, from their inception until March 28, 2017, and retrieved with the following search terms: hypertension and acupuncture, limited in spontaneously hypertensive rats (SHRs), stress-induced (or cold-induced) hypertensive or pre-hypertensive models. We find that, in these hypertensive animals, acupuncture could mainly influence factors related to the nervous system, oxidative stress, the endocrine system, cardiovascular function, and hemorheology, which are closely associated with the stroke outcome. This trend may give us a hint that acupuncture might well participate in the secondary prevention of stroke through these pathways when used in the management of hypertension.

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“…In our case reports, we used acupuncture alone to effectively control the blood pressure at the target level in the stroke patients until follow-up at 2 or 3 months after finishing treatments, which differs from one of the published randomized controlled trials in which the acupuncture effect on blood pressure disappeared at 3 months after finishing treatments [11], but the side effects-eliminating phenomenon caused by acupuncture is also seen in other studies [7,12].…”

Section: Discussionmentioning

confidence: 56%

“…The acupoints were as follows: bilateral ST9 (Renying), LI4 (Hegu), LI11 (Quchi), ST36 (Zusanli), and LR3 (Taichong). Manipulations were identical to those described in a published article [7]. LR3 was needled in the same way as LI4.…”

Section: Treatmentmentioning

confidence: 99%

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Acupuncture for Blood Pressure Control in Stroke Patients: Case Reports

Zheng

Zhao

et al. 2016

Complement Med Res

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Background: Effective control of hypertension is deeply associated with the secondary prevention of stroke. The blood pressure-lowering effect of acupuncture alone is controversial but worthy of exploration, considering the side effects of and the problems of low adherence to drugs. Case Reports: One male patient experienced severe dizziness after overuse of valsartan, which decreased his blood pressure to 110/70 mm Hg. Our acupuncture treatment of 40 sessions alone regulated his blood pressure to about 110/70-130/80 mm Hg, with disappearance of the dizziness after 3 sessions. The second male patient with a suboptimal blood pressure during treatment with 50 mg/day of irbesartan received sole acupuncture treatment of 41 sessions, which decreased his blood pressure to about 120/70-130/80 mm Hg after 6 sessions. The third patient, who refused to take antihypertensive drugs because of their side effects, received acupuncture treatment of 46 sessions over 2 months, which reduced his blood pressure from 150/90 to 120/80 mm Hg. The efficacy continued for 3 months (cases 1 and 3) or 2 months (case 2) post treatment end. Conclusion: Our cases suggest the potential of acupuncture alone to favorably control high blood pressure or regulate low blood pressure in stroke individuals, as a means of secondary prevention of stroke.

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Acupuncture Treatment for Hypertension: A Case Study

Cited by 12 publications

References 7 publications

Acupuncture lowering blood pressure for secondary prevention of stroke: a study protocol for a multicenter randomized controlled trial

Acupuncture lowering blood pressure for secondary prevention of stroke: a study protocol for a multicenter randomized controlled trial

Regulation of Hypertension for Secondary Prevention of Stroke: The Possible ‘Bridging Function' of Acupuncture

Acupuncture for Blood Pressure Control in Stroke Patients: Case Reports

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