Acute Aggravation of Subdural Effusion Associated with Pachymeningitis Carcinomatosa: Case Report

Abstract

The authors present a case of acute aggravation of subdural effusion associated with pachymeningitis carcinomatosa. Microscopic examination of a surgical specimen revealed diffuse involvement of the dura mater by a metastatic adenocarcinoma in which the tumor cells invaded venules located in the areolar layer in particular. The rapid increase in capillarv transmural pressure resulted in extravasation of plasma components, causing an increase in subdural effusion.

Malignant subdural effusion associated with disseminated adenocarcinoma: a case report

“…The most common neoplasms associated with dural metastases are breast cancer, melanoma, gastrointestinal and prostate cancer [ 7 ]. The lesions often remain clinically asymptomatic [ 8 ], but they may become symptomatic due to mass effect or developing different kinds of subdural fluid from acute or chronic hematoma to malignant effusion [ 5 , 9 , 10 ]. Chronic subdural hematoma resulting from neoplastic invasion of the meninges is uncommon, with the incidence being about 0.5 – 4% of all intracranial metastases [ 6 ].…”

“…Chronic subdural hematoma resulting from neoplastic invasion of the meninges is uncommon, with the incidence being about 0.5 – 4% of all intracranial metastases [ 6 ]. Metastaic subdural effusion is even scarcer, and to our best knowledge few cases of such condition have been reported beforehand [ 5 , 10 ].…”

“…Subdural effusion may occur following different situations such as bacterial meningitis, head injury and certain surgical procedures such as transventricular approaches or endoscopic third ventriculostomy [ 1 - 4 ]. However, subdural effusion in the setting of dural metastasis is very rare and to our knowledge limited cases have been reported [ 5 ].…”

Malignant subdural effusion associated with burkitt lymphoma

“…Subdural effusion occurs by several pathogenesis such as head injury, meningitis and post brain surgical procedures, and so on [1][2][3]. However, subdural effusion by metastatic malignant tumors is very rare [4]. The common malignant tumors associated with subdural effusion are breast cancer and stomach cancer [5][6].…”