Acute and Chronic Chorea in Childhood

Gilbert, Donald L.

doi:10.1016/j.spen.2009.03.009

Cited by 28 publications

(23 citation statements)

References 39 publications

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“…On the basis of the negative serology and normal blood cell count, ESR and CRP, an infectious cause was less likely in our patient. Several autoimmune diseases (such as systemic lupus erythematosus, central nervous system vasculitis and the antiphospholipid syndrome) can cause childhood chorea 12 13. However, our patient had no additional symptoms, negative ANA and ANCA screening and negative antiphospholipid antibodies.…”

Section: Differential Diagnosismentioning

confidence: 61%

“…Infectious causes include central nervous system infections with herpes simplex virus, varicella-zoster virus, mycoplasma and, rarely, infections with HIV or spirochetes 12 13. On the basis of the negative serology and normal blood cell count, ESR and CRP, an infectious cause was less likely in our patient.…”

Section: Differential Diagnosismentioning

confidence: 66%

“…SC is the most common cause of childhood chorea,1 but there is an extensive differential diagnosis, including infections, autoimmunity, endocrine disorders, intoxications, intracerebral (vascular) lesions and inherited diseases 12 13. Infectious causes include central nervous system infections with herpes simplex virus, varicella-zoster virus, mycoplasma and, rarely, infections with HIV or spirochetes 12 13.…”

Section: Differential Diagnosismentioning

confidence: 99%

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Successful treatment of Sydenham's chorea with intravenous immunoglobulin

et al. 2016

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We present a case of a 10-year-old girl diagnosed with Sydenham's chorea. Despite treatment with haloperidol and valproic acid for 2 weeks and antibiotics for 5 days, her symptoms continued to worsen. She became severely impaired in daily functioning, as she could barely speak or walk, experienced major feeding difficulties and required help with all daily activities. She was treated with intravenous immunoglobulin (IVIG). Within 4 days, her symptoms started to improve and after 1-month she had fully recovered. This case reminds us that Sydenham's chorea can result in major functional impairment. There is some evidence on the beneficial effect of IVIG in the treatment of Sydenham's chorea, as is evident in our case. Therefore, IVIG should be considered as a treatment option in patients with severe chorea.

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Section: Differential Diagnosismentioning

confidence: 61%

Section: Differential Diagnosismentioning

confidence: 66%

Section: Differential Diagnosismentioning

confidence: 99%

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Successful treatment of Sydenham's chorea with intravenous immunoglobulin

et al. 2016

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“…The management of stimulant-induced chorea has not been well established. In most of the available literature, stopping the offending agent and, if necessary based on severity of symptoms, administration of dopamine blocking agents or benzodiazepines have been recommended [21]. However, the continuation of ADHD treatment has not been mentioned.…”

Section: Discussionmentioning

confidence: 99%

Methylphenidate-induced Exacerbation of Chorea in a Child Resolved with Switching to Atomoxetine

Ekinci

Yaşöz

Baş

et al. 2020

Clin Psychopharmacol Neurosci

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“…However, the clinical course and response to medication is variable, and the nature, severity, and duration of impact on daily life are poorly understood. Some authors suggest that as spontaneous remission is expected after a few months, occupational therapy and physiotherapy are not indicated 9. Functional long-term issues and safe hospital discharge, while florid movements are still present, have however not been described.…”

Section: Introductionmentioning

confidence: 99%