Acute and chronic pain management in sport medicine: an expert opinion looking at an alternative mechanism-based approach to the pharmacological treatment

Fanelli, Andrea; Laddomada, Tommaso; Sacchelli, Massimiliano; Allegri, Massimo

doi:10.23736/s0375-9393.22.16924-5

Cited by 2 publications

(1 citation statement)

References 66 publications

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“…Inadequate intra-operative analgesia may contribute to accidental awareness of pain and postoperative complications [3,4]. Excessive analgesia may increase the rate of postoperative hyperalgesia [5,6]. Various devices intended to monitor nociception and guide analgesic dosing have been developed [7].…”

Section: Introductionmentioning

confidence: 99%

A randomised controlled trial of the analgesia nociception index for intra‐operative remifentanil dose and pain after gynaecological laparotomy

et al. 2023

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We aimed to investigate the effect of the analgesia nociception index on postoperative pain. We randomly allocated 170 women scheduled for gynaecological laparotomy and analysed results from 159: in 80 women, remifentanil was infused to maintain analgesia nociception indices 50-70; and in 79 women, remifentanil was infused to maintain systolic blood pressure < 120% of baseline values. The primary outcome was the proportion of women with pain scores ≥ 5 (scale 0-10) within 40 min of admission to recovery. The proportion of women with pain scores ≥ 5 was 62/80 (78%) vs. 64/79 (81%), p = 0.73. Mean (SD) doses of fentanyl in recovery were 53.6 (26.9) lg vs. 54.8 (20.8) lg, p = 0.74. Intra-operative remifentanil doses were 0.124 (0.050) lg.kg À1 .min À1 vs. 0.129 (0.044) lg.kg À1 .min À1 , p = 0.55.

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