Acute and critically ill peripartum cardiomyopathy and 'bridge to' therapeutic options: a single center experience with intra-aortic balloon pump, extra corporeal membrane oxygenation and continuous-flow left ventricular assist devices

Gevaert, Sofie; Belleghem, Yves Van; Bouchez, Stefaan; Herck, Ingrid; Somer, Filip De; Block, Yasmina De; Tromp, Fiona; Vandecasteele, Els; Martens, F; Pauw, Michel De

doi:10.1186/cc10098

Cited by 86 publications

(51 citation statements)

References 27 publications

(24 reference statements)

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“…Inotropes, intra-aortic balloon pumps, LV and biventricular assist devices, and extracorporeal membrane oxygenation should be considered in these cases and have been used successfully. [75][76][77][78][79] Aggressive treatment should generally be sought in light of the frequent recovery of patients with PPCM. When recovery does not occur, cardiac assist devices can serve as a bridge to transplantation.…”

Section: Cardiac Assist Devicesmentioning

confidence: 99%

Peripartum Cardiomyopathy

2016

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Abstract-Peripartum cardiomyopathy is a potentially life-threatening pregnancy-associated disease that typically arises in the peripartum period and is marked by left ventricular dysfunction and heart failure. The disease is relatively uncommon, but its incidence is rising. Women often recover cardiac function, but long-lasting morbidity and mortality are not infrequent. Management of peripartum cardiomyopathy is largely limited to the same neurohormonal antagonists used in other forms of cardiomyopathy, and no proven disease-specific therapies exist yet. Research in the past decade has suggested that peripartum cardiomyopathy is caused by vascular dysfunction, triggered by late-gestational maternal hormones. Most recently, information has also indicated that many cases of peripartum cardiomyopathy have genetic underpinnings. We review here the known epidemiology, clinical presentation, and management of peripartum cardiomyopathy, as well as the current knowledge of the pathophysiology of the disease.

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Section: Cardiac Assist Devicesmentioning

confidence: 99%

Peripartum Cardiomyopathy

2016

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“…48,50 Extracorporeal membrane oxygenation can also serve as a bridge to left ventricular assist devices in patients with refractory cardiogenic shock despite use of an intraaortic balloon pump and full inotropic support. 51 Women in whom maximal medical management is unsuccessful may be candidates for cardiac transplantation. 48 According to one study, 14 cardiac transplantation was necessary in 4% of women with PPCM.…”

Section: Decompensated Heart Failurementioning

confidence: 99%

Peripartum Cardiomyopathy: Review and Practice Guidelines

Johnson-Coyle

Jensen

Sobey

2012

American Journal of Critical Care

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Peripartum cardiomyopathy, a type of dilated cardiomyopathy of unknown origin, occurs in previously healthy women in the final month of pregnancy and up to 5 months after delivery. Although the incidence is low-less than 0.1% of pregnancies -morbidity and mortality rates are high at 5% to 32%. The outcome of peripartum cardiomyopathy is also highly variable. For some women, the clinical and echocardiographic status improves and sometimes returns to normal, whereas for others, the disease progresses to severe cardiac failure and even sudden cardiac death. In acute care, treatment may involve the use of intravenous vasodilators, inotropic medications, an intra-aortic balloon pump, ventricular-assist devices, and/or extracorporeal membrane oxygenation. Survivors of peripartum cardiomyopathy often recover from left ventricular dysfunction; however, they may be at risk for recurrence of heart failure and death in subsequent pregnancies. Women with chronic left ventricular dysfunction should be managed according to guidelines of the

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“…Peripartum cardiomyopathy is a rare disease affecting women in the last month of their pregnancy or up to five months after delivery; it affects one in every 3000 to 4000 live births in the US each year [1]. It was first described by Demakis in year 1971 [2].…”

Section: Introductionmentioning

confidence: 99%

“…Extra corporeal membrane oxygenation (ECMO) can be used as a short term temporary support for emergency rescue in patients with refractory cardiogenic shock. Only few reports exist about the place of LVAD and ECMO in severe refractory cardiomyopathy [1].…”

mentioning

confidence: 99%

“…Patients refractory to medical therapy and intra-aortic balloon pump (IABP) counterpulsation or in whom weaning from these therapies is impossible, are candidates for a left ventricular assist device (LVAD) as a bridge to recovery or transplant [1]. Extra corporeal membrane oxygenation (ECMO) can be used as a short term temporary support for emergency rescue in patients with refractory cardiogenic shock.…”

mentioning

confidence: 99%

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Interest of Ventricular Assist Device in Peripartum Cardiomyopathy, a Case Report and Review Article*

Hamdan¹,

Nassar²,

Zein³

et al. 2013

WJCS

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We report a case of severe post partum cadiomyopathy in severe cardiogenic shock, treated successfully and urgently with the implantation of Left Ventricular Assist device. The patient recovered a normal left ventricle function shortly after implantation. This case illustrates the crucial place of left ventricular assist device in severe post partum cardiomyopathy as a bridge to recovery as well as a bridge to transplantation.

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Acute and critically ill peripartum cardiomyopathy and 'bridge to' therapeutic options: a single center experience with intra-aortic balloon pump, extra corporeal membrane oxygenation and continuous-flow left ventricular assist devices

Cited by 86 publications

References 27 publications

Peripartum Cardiomyopathy

Peripartum Cardiomyopathy

Peripartum Cardiomyopathy: Review and Practice Guidelines

Interest of Ventricular Assist Device in Peripartum Cardiomyopathy, a Case Report and Review Article*

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