Acute and late clinical outcome after rotational atherectomy for complex coronary disease

Gender differences in acute and 30‐day outcomes after orbital atherectomy treatment of de novo, severely calcified coronary lesions

“…In terms of angiographic complications, there was no difference in the rates of perforation, slow flow/no reflow, and abrupt closure in females and males in the ORBIT II study. The reported 3.4% overall severe dissection rate in the ORBIT II study was low in comparison to severe dissection rates (type C–F) reported in rotational atherectomy studies and is similar to the 3.3% dissection rate reported in the contemporary ROTAXUS study . Despite adjusting for baseline covariates, a higher rate of overall severe dissection persisted in females compared to males.…”

2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

“…Although the technical safety and efficacy of atheroablative and thrombectomy devices have been described, few data exist to demonstrate incremental benefit with regard to clinical outcomes, and even less information is available that describes the use of these strategies specifically in patients with UA/NSTEMI. 587 The need to continue with the development of safer, more effective PCI techniques is emphasized by recently raised concerns about delayed endothelialization over DES and consequent increases in late coronary thrombotic events, potentially leading to death or MI. 399,400,402,403,411 Other techniques and devices, such as the AngioJet thrombectomy catheter, have been tested for the treatment of thrombi that are visible within a coronary artery.…”

Beneficial effect of rotational atherectomy with low platform speed on late outcomes

“…For example, in a randomized trial comparing conventional balloon angioplasty with RA for type B2 lesions, no difference in restenosis rates was noted [8]. Despite many years of widespread application of RA, the technique is open to very subjective bias and its results are very variable [9,10]. Modification of procedures has therefore been proposed, such as providing a more adequate burr/artery ratio, eliminating the wire bias and infusion of rota-flush [11 -13].…”