Acute bronchiolitis and respiratory syncytial virus seasonal transmission during the COVID-19 pandemic in Spain: A national perspective from the pediatric Spanish Society (AEP).

Torres-Fernandez, David; Casellas, Aina; Mellado, María José; Calvo, Cristina; Bassat, Quique

doi:10.1016/j.jcv.2021.105027

Cited by 35 publications

(37 citation statements)

References 17 publications

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“…The protective role of breastfeeding against bronchiolitis is particularly relevant during actual coronavirus disease 2019 (COVID-19) pandemic. In 2020, a dramatic reduction in RSV bronchiolitis hospitalization was reported worldwide, coinciding with the spread of SARS-CoV-2 infection [ 70 , 71 , 72 ]. The most accredited hypothesis to explain this uncommon finding was that the strict adoption of non-pharmaceutical interventions to contain SARS-CoV-2 diffusion (including handwashing and social distancing) also reduced the circulation of other infectious agents, such as RSV [ 71 ].…”

Section: Breastfeeding and Infectionsmentioning

confidence: 99%

Exclusive Breastfeeding and Vitamin D Supplementation: A Positive Synergistic Effect on Prevention of Childhood Infections?

Domenici¹,

Vierucci²

2022

IJERPH

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Human milk is the best food for infants. Breastfeeding has been associated with a reduced risk of viral and bacterial infections. Breast milk contains the perfect amount of nutrients needed to promote infant growth, except for vitamin D. Vitamin D is crucial for calcium metabolism and bone health, and it also has extra-skeletal actions, involving innate and adaptive immunity. As exclusive breastfeeding is a risk factor for vitamin D deficiency, infants should be supplemented with vitamin D at least during the first year. The promotion of breastfeeding and vitamin D supplementation represents an important objective of public health.

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Section: Breastfeeding and Infectionsmentioning

confidence: 99%

Exclusive Breastfeeding and Vitamin D Supplementation: A Positive Synergistic Effect on Prevention of Childhood Infections?

Domenici¹,

Vierucci²

2022

IJERPH

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“…Two studies from Spain and France were multicentric 16,18 . The highest number of symptomatic cases were admitted in the multicentric study from Spain 16 before the pandemic in 2019 and during the pandemic.…”

Section: Included Studiesmentioning

confidence: 99%

“…These studies reported 7691 laboratory-confirmed RSV associated lower respiratory tract infections in 2019 and 4964 during the pandemic in 2020/21. Two studies from Spain and France were multicenteric [16,18]. The highest number of symptomatic cases were admitted in the multicentric study from Spain [16] before the pandemic in 2019 and during the pandemic.…”

Section: Included Studiesmentioning

confidence: 99%

“…Two studies from Spain and France were multicenteric [16,18]. The highest number of symptomatic cases were admitted in the multicentric study from Spain [16] before the pandemic in 2019 and during the pandemic. All the studies chosen for the meta-analysis reported a decrease in bronchiolitis cases with increased RSV positivity during the pandemic.…”

Section: Included Studiesmentioning

confidence: 99%

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The impact of COVID-19 pandemic on bronchiolitis (lower respiratory tract infection) due to respiratory syncytial virus: A systematic review and meta-analysis

Sabeena¹,

Ravishankar

Robin

et al. 2022

Preprint

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Objective This systematic review and meta-analysis aimed to quantitatively evaluate the effect of the COVID-19 pandemic on respiratory syncytial virus (RSV) associated bronchiolitis among hospitalised infants. Methods The study protocol was registered in the PROSPERO database (CRD42022314000) and was designed based on PRISMA guidelines updated in May 2020. The meta-analysis component was modified appropriately to synthesise the pooled proportion of infants having RSV-associated bronchiolitis before the COVID-19 pandemic in 2019 and during the pandemic with 95% confidence interval (CI). Results: The eight qualified studies for the meta-analysis were from Spain, Italy, France and China, including 109,186 symptomatic cases of bronchiolitis before the pandemic in 2019 and 61,982 cases in 2020-2021. The quantitative analysis included laboratory-confirmed RSV infection in 7691 infants with bronchiolitis reported before the pandemic in 2019. Meanwhile, during the pandemic, 4964 cases were associated with RSV infection. The pooled proportion of RSV-associated bronchiolitis cases before the pandemic in 2019 was 16.74% (95% CI 11.73-22.43%). The pooled proportion of confirmed RSV cases during the pandemic in 2020/2021 was 19.20 % (95% CI 12.01-27.59%). Conclusion There was an increase in RSV activity after the relaxation of stringent public health measures during the COVID-19 pandemic.

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“…It is likely that the lockdown measures and behavioral interventions to reduce SARS-CoV-2 transmission in Spain during 2020-2021 also impacted on CMV transmission and cCMV prevalence. In fact, a dramatic decrease in respiratory syncytial virus infections in the 2020 winter season [5] and a re-emergence of enterovirus D68 after easing the lockdown in 2021 [6] have also been reported, both viruses sharing the contact transmission route with CMV. We agree with Fernandez et al [1] that our findings reinforce the role of behavioral risk reduction interventions to prevent cCMV in pregnant women.…”

mentioning

confidence: 99%

Letter to the Editor on the original article: Lower prevalence of congenital cytomegalovirus infection in Portugal: possible impact of COVID-19 lockdown?

et al. 2022

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Abbreviations cCMV Congenital Cytomegalovirus infection Dear Editor, We read with interest the article by Fernandez et al. [1], in which the authors describe an eightfold decrease (from 0.67 to 0.078%) in the prevalence of congenital Cytomegalovirus infection (cCMV) in Portugal during the COVID-19 pandemic. We would like to share the preliminary results of an ongoing universal screening study of cCMV in Hospital Sant Joan de Déu (Barcelona, Spain). The study was approved by the local Ethics Committee (ref. PIC-205-19); informed consent from parents is obtained at inclusion. cCMV screening is performed in saliva samples, obtained using flocked swabs (catalog no. 300267, Deltalab; Rubí, Spain) in the first 14 days of life, by means of the Alethia CMV DNA amplification assay (Meridian Bioscience; Cincinnati, OH) [2]; confirmation of cCMV is performed Communicated by Peter de Winter Antoni Noguera-Julian and Ana Alarcón contributed equally to this work.

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Acute bronchiolitis and respiratory syncytial virus seasonal transmission during the COVID-19 pandemic in Spain: A national perspective from the pediatric Spanish Society (AEP).

Cited by 35 publications

References 17 publications

Exclusive Breastfeeding and Vitamin D Supplementation: A Positive Synergistic Effect on Prevention of Childhood Infections?

Exclusive Breastfeeding and Vitamin D Supplementation: A Positive Synergistic Effect on Prevention of Childhood Infections?

The impact of COVID-19 pandemic on bronchiolitis (lower respiratory tract infection) due to respiratory syncytial virus: A systematic review and meta-analysis

Letter to the Editor on the original article: Lower prevalence of congenital cytomegalovirus infection in Portugal: possible impact of COVID-19 lockdown?

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