Acute Carpal Tunnel Syndrome Secondary to Amyloidosis

Abstract

Introduction ACTS secondary to amyloidosis is a very rare situation in the literature, and here, we present a unique case of ACTS secondary to amyloidosis. Case Report A 61-year-old male patient was admitted to our hospital with complaints of numbness in the lateral half of his 1, 2, 3, and 4 fingers of his right hand. These complaints started acutely, and the patient did not have a history of trauma. His clinical examination was suitable for acute carpal tunnel syndrome. Discussion Carpal tunnel syndrome, as well as acute carpal tunnel syndrome, may occur based on different causes. ACTS is very rare, especially when it is not caused by a trauma. Here, we presented a unique case of ACTS based on amyloidosis. Conclusion It should be kept in mind when ACTS may occur in patients with the diagnosis of amyloidosis.

A Case of Atraumatic Acute Carpal Tunnel Syndrome Requiring Emergency Surgery

“…ACTS is often caused by trauma, such as distal radius fracture and carpal fracture, and non-traumatic onset is relatively rare [2]. Infection, bleeding, amyloidosis, and radiation have been cited as causes of non-traumatic onset [3][4][5][6][7]. In our case, the patient had chronic synovitis due to rheumatoid arthritis; external physical force was applied by the hand to induce acute inflammation, and the pressure inside the carpal tunnel rose sharply, causing ACTS.…”

Acute carpal tunnel syndrome as first presentation of amyloidosis: a case report

“…There is one report in the literature of acute CTS secondary to localised amyloid deposits in the carpal tunnel. 2 Unlike this case, that patient had a recent biopsy from an alternative site demonstrating findings consistent with secondary amyloidosis. The definitive method for diagnosis of amyloidosis is tissue biopsy.…”

“…There is a paucity in the literature linking amyloidosis with cases of acute CTS-we were able to find only one case report in the English literature demonstrating a case of acute CTS secondary to amyloidosis. 2 Chronic CTS is a common neuropathy encountered in clinical practice and symptoms progress over months to years, whereas the features of acute CTS progress over hours and days. Acute CTS is characterised by rapid progression of pain and paraesthesia in the distribution of the median nerve.…”

“…1 Amyloidosis is known to be associated with chronic CTS but rarely manifests in acute cases of CTS. 2 This case report describes an unusual presentation of acute CTS secondary to amyloidosis requiring urgent surgical decompression.…”