2002
DOI: 10.5144/0256-4947.2002.167
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Acute Chest Syndrome in Sickle Cell Disease in Saudi Arab Children in the Eastern Province

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Cited by 10 publications
(16 citation statements)
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“…These results support the theory that SCD patients in Eastern province has in general a milder disease -Avascular necrosis of femoral head and splenic complications are exceptions with less frequent ACS crisis, most likely due to high prevalence of Asian haplotype among SCD patients in this area,[5182127–30] coexisting alpha-thalassaemia,[3132] persistence of high Hb-F levels,[3334] haematology, social circumstances and geographical and climatic variation. [435]…”
Section: Discussionsupporting
confidence: 71%
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“…These results support the theory that SCD patients in Eastern province has in general a milder disease -Avascular necrosis of femoral head and splenic complications are exceptions with less frequent ACS crisis, most likely due to high prevalence of Asian haplotype among SCD patients in this area,[5182127–30] coexisting alpha-thalassaemia,[3132] persistence of high Hb-F levels,[3334] haematology, social circumstances and geographical and climatic variation. [435]…”
Section: Discussionsupporting
confidence: 71%
“…I studied the summation of results in this study together with those done in Qatif and Hofuf previously[2123] versus the results reported by Taylor, et al and Bernard Maitre, et al [2425] Tables 2 and 3. I found that recurrence is significantly lower ( P <0.025) in patients from Eastern province compared to patients with African haplotype, mortality also is lower but not statistically significant [Figure 2].…”
Section: Resultsmentioning
confidence: 93%
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“…Painful crises are the primary reason for these patients to seek medical care in hospital emergency departments (Yale et al, 2000). Acute chest syndrome (ACS) is another common complication of vaso-occlusion in patients with SCA, accounting for more than 90% of hospital admission and causing significant morbidity and mortality (Al-Dabbous, 2002). The term ACS was first suggested in 1979 by Charache et al and was developed in order to reflect the unique nature of acute pulmonary illness in patients with SCA.…”
Section: Introductionmentioning
confidence: 99%