Acute cholinergic syndrome following ingestion of contaminated herbal extract

Hsieh, Ming‐Ju; Yen, Zui-Shen; Chen, Shyr‐Chyr

doi:10.1136/emj.2008.060889

Cited by 5 publications

(3 citation statements)

References 4 publications

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“…This has influenced many of pharmaceutical companies to produce new antimicrobial formulations extracted from plants. Herbs are from natural plants and therefore often considered harmless compared with western medicines [73]. Plant species still serve as a rich source of 147 many novel biologically active compounds.…”

Section: Resultsmentioning

confidence: 99%

Phytochemical Constituents, Antibacterial and Antioxidant Activities of some Medicinal Plants

Aldesuquy

2018

CTBEB

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The present study provides a detailed description of the phytochemical analysis, physiological features and biological activities of four selected plant species, namely Calligomum polygnoides subsp. comosum and Nicotiana glauca collected from the coastal desert in the Delatic Mediterranean Sea, as well as Hyoscyamus muticus and pulicaria undulate subsp. Undulata collected from the inland desert in Wadi Hagul and Wadi El-Molaak in the North of Eastern Desert in Egypt. The obtained results showed that, the studied plant species are relatively rich in proximate constituents, elements and bioactive secondary metabolites. Hyscyamus muticus leaves appeared to accumulate ABA in highest magnitude if compared to Nicotiana glauca, Pulicaria undulata subsp. undulata and Calligonum Polygonoides subsp. comosum. Antioxidant enzymes as well as DPPH scavenging activities in leaves of Nicotiana glauca, found to be the highest activity in catalase, perioxidase and polyphenol oxidase as well as antioxidant activity and IC50 as compared to other selected plant species. On the other hand, Calligonum polygonoides subsp. comosum attained the highest activity of phenylalanine ammonia lyase and the weakest antioxidant activity with IC50 value (0.29 mg ml -1 ).The highest ratio of total saturated fatty acids to unsaturated fatty acids was recorded in Nicotiana glauca, while the lowest one was found in Calligonum polygonoides subsp. comosum. Concerning the biological activities, the methanolic extract of Nicotiana glauca showed the highest antioxidant activity, while the extract of Calligomum polygnoides subsp. comosum exhibited the weakest antioxidant activity. The methanolic extract of Pulicaria undulata subsp. undulata showed the highest antimicrobial activity, followed by the extracts of Hyoscyamus muticus, Nicotiana glauca and finally by Calligomum polygnoides subsp. comosum. On the other hand, the aqueous extract of Nicotiana glauca showed, the highest inhibition percentages of seed germination, radical growth and plumule growth of summer weed Portulaca oleracea, followed by the extracts of Pulicaria undulata subsp. undulata, Hyoscyamus muticus and finally by Calligomum polygnoides subsp. comosum. Therefore, it can be concluded that, the selected plant species in the present study are obviously considered as tolerant species against extreme drought and salinity. These species could be also used as natural renewable resources in numerous beneficial purposes such as medicine industry, natural antioxidants, antimicrobial agents and allopathic potential for biological control of weeds.

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Section: Resultsmentioning

confidence: 99%

Phytochemical Constituents, Antibacterial and Antioxidant Activities of some Medicinal Plants

Aldesuquy

2018

CTBEB

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“…According to a survey by NCI, USA, 61% of the 877 small-molecule new chemical entities introduced as drugs worldwide during 1981-2002 were inspired by natural products [3] . In USA, herbal preparations are becoming more popular and used increasingly [4] . There is a long history of medicinal use of plants in Asian countries, some of which have proved useful to humans as pharmaceuticals.…”

Section: Introductionmentioning

confidence: 99%

“…This has influenced many of pharmaceutical companies to produce new antimicrobial formulations extracted from plants or herbs. Herbs are from natural plants and therefore often considered to be harmless compared with western medicines [4] . Plant species still serve as a rich source of many novel biologically active compounds.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Research in Asia in the Period from 2000-2008

Hafidh¹,

Abdulamir²,

Bakar³

et al. 2009

American J. of Pharmacology and Toxicology

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Problem statement: Plant antioxidants are natural plant products that inhibit the adverse effects of the Reactive Oxygen Species (ROS) produced in plants. Thus, antioxidants enable plants to survive. Depending on this principle, human beings started using some plants' parts to cure from diseases many centuries ago, even before the discovery of microbes or disclosing the etiology of many human diseases. Shed light on the importance of diet and natural products that have proved of great health impact on human traditionally and scientifically, disclosing the central role of natural antioxidants in this matter. Moreover, this review tried to give an overview on the research has so far done in Asian countries particularly in the field of natural antioxidants during the period 2000-2008. Therefore, the aim of this review is to present a comprehensive index for the antioxidant property of herbs and plants that have been traditionally used as well as experimentally proved beneficial in these countries. Approach: We had compared Asian and other nation's diet in the popularity of the traditional medicine and the type of daily meal in respect to their antioxidants contents and valuable health promoting effects. Many literatures had been collected using online search engines and the main library of University Putra Malaysia. The gathered data had been arranged alphabetically in a table depending on the plant's scientific name, common name, the used part(s) and the family name. Results: The research had shown that there were seventy-six plants with proved antioxidant activity which had been well studied by Asian scientists in the chosen period of time. Conclusion: The antioxidant components of the natural products constitute the major source of human health promotion and maintenance. The nature is still the perfect source for health promotion and for the supplementation of safe drugs. Great attention is mandatory from all the scientists around the world to explore many underestimated plants with highly effective antioxidant activity.

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