Acute complications following gamma knife radiosurgery are rare

Chin, Lawrence S.; Lazio, Barbara E.; Biggins, Terri F.; Amin, Pradip

doi:10.1016/s0090-3019(00)00219-6

Cited by 41 publications

(17 citation statements)

References 9 publications

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“…This is an alternative to microsurgical resection particularly in patients with increased risk of perioperative complications due to complex medical comorbidities or increased age. 18,19 Generally patients undergoing SRS/SRT can be managed without inpatient admission and there is little recovery time required postoperatively; 18,20 however, there are both short-term and long-term risks including radiation toxicity, which causes damage to neural structures resulting in facial weakness, facial numbness or dysasthesia, and impairment of hearing and balance. [21][22][23] Hydrocephalus can also occur as a late complication after radiosurgery and may require ventricular shunting.…”

Section: Introductionmentioning

confidence: 99%

Systematic review of quality of life in the management of vestibular schwannoma

Gauden¹,

Weir²,

Hawthorne³

et al. 2011

Journal of Clinical Neuroscience

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Section: Introductionmentioning

confidence: 99%

Systematic review of quality of life in the management of vestibular schwannoma

Gauden¹,

Weir²,

Hawthorne³

et al. 2011

Journal of Clinical Neuroscience

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“…In most cases radiosurgery does not require inpatient hospitalization and requires virtually no convalescence following treatment; however, short-term and long-term risks do exist with radiosurgery treatment. 31,32 In particular, stereotactic radiosurgery for the treatment of VS introduces radiation toxicity risks to adjacent neurologic structures and result in a functional threat to the facial nerve, hearing and balance. 14,16,17,23,27,30,[33][34][35][36][37][38][39][40][41] Hydrocephalus and other cranial neuropathies such as facial spasm have also been noted after radiosurgery for VS. 4,5,23,37,[42][43][44][45][46][47] Surgical shunting and cerebrospinal fluid diversion may be required to address the late hydrocephalus complication.…”

Section: Introductionmentioning

confidence: 99%

Hearing preservation after stereotactic radiosurgery for vestibular schwannoma: A systematic review

Yang

Aranda

Han

et al. 2009

Journal of Clinical Neuroscience

130

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“…GKRS as a treatment modality for VS typically does not require inpatient hospitalization, however acute and chronic complications can occur [31][32][33]. In particular, radiation toxicity of neuro-anatomic structures adjacent to the tumor may develop and manifest as impaired function of the facial nerve, hearing loss, or loss of equilibrium and balance.…”

Section: Introductionmentioning

confidence: 99%

Facial nerve preservation after vestibular schwannoma Gamma Knife radiosurgery

et al. 2009

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Objective Facial nerve preservation is a critical measure of clinical outcome after vestibular schwannoma treatment. Gamma Knife radiosurgery has evolved into a practical treatment modality for vestibular schwannoma patients, with several reported series from a variety of centers. In this study, we report the results of an objective analysis of reported facial nerve outcomes after the treatment of vestibular schwannomas with Gamma Knife radiosurgery. Materials and methods A Boolean Pub Med search of the English language literature revealed a total of 23 published studies reporting assessable and quantifiable outcome data regarding facial nerve function in 2,204 patients who were treated with Gamma Knife radiosurgery for vestibular schwannoma. Inclusion criteria for articles were: (1) Facial nerve preservation rates were reported specifically for vestibular schwannoma, (2) Facial nerve functional outcome was reported using the House-Brackmann classification (HBC) for facial nerve function, (3) Tumor size was documented, and (4) Gamma Knife radiosurgery was the only radiosurgical modality used in the report. The data were then aggregated and analyzed based on radiation doses delivered, tumor volume, and patient age. Results An overall facial nerve preservation rate of 96.2% was found after Gamma Knife radiosurgery for vestibular schwannoma in our analysis. Patients receiving less than or equal to 13 Gy of radiation at the marginal dose had a better facial nerve preservation rate than those who received higher doses (B13 Gy = 98.5% vs. [13 Gy = 94.7%, P \ 0.0001). Patients with a tumor volume less than or equal to 1.5 cm 3 also had a greater facial nerve preservation rate than patients with tumors greater than 1.5 cm 3 (B1.5 cm 3 99.5% vs. [1.5 cm 3 95.5%, P \ 0.0001). Superior facial nerve preservation was also noted in patients younger than or equal to 60 years of age (96.8 vs. 89.4%, P \ 0.0001). The average reported follow up duration in this systematic review was 54.1 ± 31.3 months. Conclusion Our analysis of case series data aggregated from multiple centers suggests that a facial nerve preservation rate of 96.2% can be expected after Gamma knife radiosurgery for vestibular schwannoma. Younger patients with smaller tumors less than 1.5 cm 3 and treated with lower doses of radiation less than 13 Gy will likely have better facial nerve preservation rates after Gamma Knife radiosurgery for vestibular schwannoma.

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Acute complications following gamma knife radiosurgery are rare

Cited by 41 publications

References 9 publications

Systematic review of quality of life in the management of vestibular schwannoma

Systematic review of quality of life in the management of vestibular schwannoma

Hearing preservation after stereotactic radiosurgery for vestibular schwannoma: A systematic review

Facial nerve preservation after vestibular schwannoma Gamma Knife radiosurgery

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