Acute coronary syndrome in young adults

Arantes, Carina; Martins, Juliana; Braga, Carlos Galvão; Ramos, Vítor; Vieira, Catarina; Gaspar, António; Salgado, Alberto; Pereira, Mark A.; Rocha, Sérgia; Correia, Adelino

doi:10.1093/eurheartj/eht309.p3134

Cited by 5 publications

(12 citation statements)

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“…21,27 Studies reported percentages as low as 2.6% and 5.8%, and as high as 8% and 11.6%; less than the 13% reported in this study. 10,13,21,27,28 Moreover; the number of young patients included in this study (308 patients) is larger than that reported by other investigators which was as low as 43 and 81 patients, and as high as 195 patients. 12,27,29 The study that reported data of more than 2000 of young patients was a 7-year nationwide registry.…”

Section: Discussioncontrasting

confidence: 78%

“…38 Furthermore; young patients have STEMI more than NSTEACS. 15,21 This study indicates that there was no difference in the prevalence of ACS or STEMI in the young and the older patients who underwent PCI. About half of the young patients in this study had single-vessel CAD, less than higher rates reaching up to 70% reported by others.…”

Section: Discussionmentioning

confidence: 76%

“…Although 45 years of age or younger is the age used more often than others; studies defined age as <35 years, <40 years, <44, <46 years, <50, and <55 years. [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] Young patients, in general, account for <12% of CAD or ACS patients. 21,27 Studies reported percentages as low as 2.6% and 5.8%, and as high as 8% and 11.6%; less than the 13% reported in this study.…”

Section: Discussionmentioning

confidence: 99%

“…[10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] Young patients, in general, account for <12% of CAD or ACS patients. 21,27 Studies reported percentages as low as 2.6% and 5.8%, and as high as 8% and 11.6%; less than the 13% reported in this study. 10,13,21,27,28 Moreover; the number of young patients included in this study (308 patients) is larger than that reported by other investigators which was as low as 43 and 81 patients, and as high as 195 patients.…”

Section: Discussionmentioning

confidence: 99%

“…12,17,35 Unlike the studies that showed lower prevalence of DM, hypertension, hypercholesterolemia and lower blood levels of high-density lipoprotein cholesterol in the young compared with older patients; this study did not show such differences, a finding we share with others. 21,36 In addition to the classical cardiovascular risk factors; physical and psychological triggers and stresses can also play an important role in the incidence of CAD and ACS in young patients. These factors, however, are not routinely addressed during admission.…”

Section: Discussionmentioning

confidence: 99%

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One year prognosis of young Middle Eastern patients undergoing percutaneous coronary interventions

et al. 2016

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Background: There is scarcity of data about the outcome in young Middle Eastern patients who undergo percutaneous coronary intervention (PCI). We sought to assess clinical and coronary angiographic features and one year outcome of young compared with older patients following PCI.Methods: Baseline clinical and coronary angiographic features and major cardiovascular events from hospital admission to one year were assessed in young patients (<45 years of age) compared with older patients (>45 years of age).Results: Of 2426 patients; 308 (12.7%) were young. Young and older patients were predominantly males (76.3% vs. 79.8%; p=0.18) and had similar prevalence of hypertension, diabetes, dyslipidemia, and cigarette smoking. There were no differences between young and older patients in the rates of acute coronary syndrome as an indication for PCI (75.6% vs. 76.1%; p=0.90). The two groups had similar prevalence of one-vessel coronary artery disease (55.2% vs. 58.1%; p=0.37) and intervention for one vessel (74.0% vs. 72.1%; p=0.53). No significant differences were observed in the incidence of in-hospital adverse events in young compared with older patients. Incidence of adverse events in young patients at one year were not different from those in older patients, including cardiac death (3.63% vs. 2.11%), stent thrombosis (3.63% vs. 2.08%), major bleeding (1.30% vs. 1.18%), and coronary revascularization (3.65% vs. 3.24%); all p=NS.Conclusions: Among Middle Eastern patients undergoing coronary intervention; 13% were 45 years of age or younger. No favourable risk profile, coronary angiographic features or cardiovascular outcome were observed in young compared with older patients.

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Section: Discussioncontrasting

confidence: 78%

Section: Discussionmentioning

confidence: 76%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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One year prognosis of young Middle Eastern patients undergoing percutaneous coronary interventions

et al. 2016

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The Risk Factors of Acute Coronary Syndrome in Young Women: A Systematic Review and Meta-Analysis

Siagian

Christianto

Angellia

et al. 2023

CCR

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Background and Aims: Acute coronary syndrome (ACS) has been one of the leading causes of mortality in the world. Despite common understanding regarding ACS as older population’s or man's disease, the number of young women affected by this condition is increasing. Many studies had assessed the risk factors of ACS, but only a few studies focused on this subpopulation. Therefore, this systematic review and meta-analysis aims to evaluate the risk factors predisposing of ACS in the young women population. Methods: Nine online databases were screened from the date of inception to September 2021, where the acquired studies were evaluated using the PRISMA statement. The inclusion criteria were case control study with women age cut-off of <50 years. The risk factors of acute coronary syndrome were analyzed using random-effect model, expressed as summary statistics of odds ratio (OR) for categorical variable and standard mean difference (SMD) for continuous data with normal distribution, with 95% confidence interval (CI). Quality assessment was conducted using the STROBE statement. Results: Seven studies with the total of 7042 patients met the inclusion criteria of this meta-analysis. Diabetes mellitus, high BMI, obesity, hypercholestrolemia, hypertension, smoking, and family history significantly increased acute coronary syndrome risk in young women. Other risk such as heavy alcohol consumption, oral contraceptive use, and postmenopausal state were associated with higher risk of ACS. Conclusion: The independent risk factors which are strongly related to ACS in young women were diabetes mellitus, hypertension, and hypercholesterolemia with odd ratios of 6.21, 5.32, and 4.07. Other risk factors which may be associated with an increased risk of ACS in young women were heavy alcohol consumption, oral contraceptive use, and postmenopausal state. Health promotion and effective intervention on this specific population regarding these risk factors can decrease young female cardiovascular morbidity and mortality as well as improved quality of life of women.

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Risk factors associated with the development of coronary artery disease in the middle age group

Hammoudi¹,

Hussein²

2023

World J. Bio. Pharm. Health Sci.

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Background: Acute coronary syndrome includes Unstable Angina and evolving Myocardial Infarction which is usually divided into ST-segment elevation Myocardial Infarction (ST-SEMI) and non- ST-segment elevation (non- ST-SEMI) or new onset Left Bundle Branch Block. Aim of the study: To assess the association between traditional risk factors and the development of cardiovascular diseases. Methods: A cross-sectional study, was conducted during the period from the 1st of January 2022 to the 1st of May 2023 at Alrusafa Directorate of Health /AL Kindy Teaching Hospital and Ibn Al-Nafees Hospital Results: The smoker patients were 48.5%, whereas 44.5% were overweight, and 18.5% of them were obese. 57.0% had hypertension, 41% had diabetes mellitus, and 41.5% had hyperlipidemia. The patients with ST-SEMI are (65.5%), while 15.5% of them had non- ST-SEMI. No significant association was obtained between the sociodemographic history and the type of ACS. Conclusion: Hypertension was the commonest prevalent disease among the patients followed by diabetes mellitus. A family history of the acute coronary syndrome is significantly associated with the type of acute coronary syndrome.

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Acute coronary syndrome in young adults

Cited by 5 publications

References 0 publications

One year prognosis of young Middle Eastern patients undergoing percutaneous coronary interventions

One year prognosis of young Middle Eastern patients undergoing percutaneous coronary interventions

The Risk Factors of Acute Coronary Syndrome in Young Women: A Systematic Review and Meta-Analysis

Risk factors associated with the development of coronary artery disease in the middle age group

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