Acute coronary syndrome-like presentation with prolonged QT interval: an unusual case of pheochromocytoma

Özyüncü, Nil; Akturk, S; Kürklü, Türkan Seda Tan; Erol, Çetin

doi:10.1136/bcr-2016-216142

Cited by 3 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ventricular tachycardia was found in 2 subjects, one of whom was TdP (10). Although ventricular arrhythmias are a rare complication of PPGLS, they can occur (11)(12)(13)(14)(15)(16). The mechanism of QT prolongation and TdP is not very clear.…”

Section: Discussionmentioning

confidence: 99%

Case Report: An Unusual Case of Pheochromocytoma

Liao

Shu²,

Liu³

et al. 2022

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

Pheochromocytoma is a benign catecholamine secreting tumor, which is rare and originates from the adrenal gland. It has been known for a wide range of clinical manifestations and can mimic other difficult-to-diagnose diseases. Here, we report a female patient with acquired long QT syndrome, which is a rare complication of pheochromocytoma. Although relatively rare, the presence of pheochromocytoma should be considered in the case of malignant arrhythmias and electrocardiographic changes in patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Case Report: An Unusual Case of Pheochromocytoma

Liao

Shu²,

Liu³

et al. 2022

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

show abstract

“…The prolongation of the corrected QT interval has been reported in 16% to 35% of patients with pheochromocytoma [ 15 , 16 ]. A prolonged QT interval favors the occurrence of malignant ventricular arrythmias, such as ventricular tachycardia, and even ventricular fibrillation, especially torsade de pointes responsible for syncopes or cardiac arrest [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

Unusual Cardiac Manifestations of a Pheochromocytoma in a Girl

et al. 2023

View full text Add to dashboard Cite

We report the case of an 11-year-old girl who complained about severe asthenia, orthostatic dizziness and abdominal pain for 4 weeks. The primary investigation concluded on febrile urinary tract infection treated by antibiotics. Symptom persistence prompted cardiological and endocrinological investigations. A fluctuation in blood pressure, long QT interval, dilation of the aortic root and left ventricular hypertrophy were documented. Elevated levels of urinary catecholamines together with the presence of a right-sided adrenal mass shown via abdominal ultrasound and magnetic resonance imaging were highly suggestive of a pheochromocytoma. This was confirmed by through iodine-123-metaiodobenzylguathdine ([123I]-mIBG) scintigraphy. Genetic analysis allowed for the exclusion of pathogenic mutations in genes implicated in hereditary paragangliomas and pheochromocytomas but showed a rare somatic mutation in exon 3 of the von Hippel-Lindau gene. The patient was treated with a β-blocker and calcium channel antagonist and underwent laparoscopic right-sided adrenalectomy. Cardiac manifestations resolved soon after surgery indicating that they were secondary to the pheochromocytoma. After 5 years of follow-up, the patient remains asymptomatic without any sign of tumor recurrence. The presence of aortic root dilation, a prolonged QT-interval and left ventricular hypertrophy may be early cardiac manifestations of a pheochromocytoma in a child and should prompt this diagnosis to be evoked.

show abstract

“…Previously, Ozyuncu et al. ( 13 ) reported the dynamic ECG changes that occurred daily after the pheochromocytoma attack. We also found that the QT prolongation and T-wave inversions on the second day of admission were more significant than that at arrival.…”

Section: Discussionmentioning

confidence: 99%

Pheochromocytoma Mimicking Acute Coronary Syndrome: A Case Report

2022

View full text Add to dashboard Cite

Pheochromocytoma is a rare catecholamine-secreting tumor with highly variable clinical presentations. We herein report a patient who presented to the emergency department with precordia pain, elevated myocardial enzymes, T-wave inversions on electrocardiogram and segmental ventricular wall motion abnormalities on echocardiography, which is normally managed as suspected acute coronary syndrome (ACS). However, the urgent coronary angiography showed normal coronary arteries. During his hospital stay, a sudden increase in blood pressure allowed us to suspect a pheochromocytoma, which was confirmed by elevated levels of catecholamines and by the finding of a right adrenal mass on magnetic resonance imaging. The tumor was successfully excised and the patient is now asymptomatic. This case illustrates that pheochromocytoma can present as a mimic of ACS but this is often difficult to diagnose at first glance and often misleads clinicians into making an incorrect diagnosis. In addition, clinicians should be familiar with clinical manifestations of pheochromocytoma, which can help raise clinical suspicion and facilitate the early diagnosis and treatment of pheochromocytoma.

show abstract

Acute coronary syndrome-like presentation with prolonged QT interval: an unusual case of pheochromocytoma

Cited by 3 publications

References 7 publications

Case Report: An Unusual Case of Pheochromocytoma

Case Report: An Unusual Case of Pheochromocytoma

Unusual Cardiac Manifestations of a Pheochromocytoma in a Girl

Pheochromocytoma Mimicking Acute Coronary Syndrome: A Case Report

Contact Info

Product

Resources

About