Hair dyeing has been popular since ancient times, when pigments were mainly extracted from plants. With the development of technology and cultural trends, the search began not only for new pigments but also for new substances, which would make hair dyeing more durable and intense. The addition of synthetic compounds to the composition of hair coloring cosmetics, in addition to the indicated benefits also resulted in side effects. The most often listed substances with toxic properties are PPD (p-phenylenediamine), PTD (p-toluenediamine), persulfates (e.g. sodium persulfate), lavson, m-aminophenol or resorcinol. The adverse effects of these substances on the organism of the client or the hairdresser may manifest in the form of skin redness, swelling, purulent rash, urticaria or even chemical leucoderma, asthma or rhinitis.