Acute diplopia in the pediatric Emergency Department. A cohort multicenter Italian study

Raucci, Umberto; Parisi, Pasquale; Vanacore, Nicola; Penna, Francesco La; Ferro, Valentina; Calistri, Lucia; Bondone, Claudia; Midulla, Fabio; Suppiej, Agnese; Falsaperla, Raffaele; Cordelli, Duccio Maria; Palmieri, Antonella; Verrotti, Alberto; Becciani, Sabrina; Aguzzi, Sonia; Mastrangelo, Mario; Pelizza, Federica; Greco, Filippo; Carbonari, Giulia; Tallone, Ramona; Bottone, Gabriella; Trenta, Italo; Masi, Stefano; Villa, Maria Pia; Reale, Antonino

doi:10.1016/j.ejpn.2017.05.010

Cited by 5 publications

(1 citation statement)

References 16 publications

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“…34 Fluctuating weakness of ocular, facial, limb, bulbar, and respiratory muscles associated with an increasing fatigability may represent the initial presentation of myasthenia gravis while acute diplopia may be caused by different life-threatening conditions (including brain tumors, demyelinating conditions, idiopathic intracranial hypertension, and major posttraumatic diseases) in about one fifth of the cases. 34,37 ADEM should be suspected in children presenting with multifocal neurological dysfunctions and signs of encephalopathy following recent viral infections or, less frequently, vaccinations. 34 MRI features (hyperintensity on T2-and fluid-attenuated inversion recovery [FLAIR]-weighted images caused by large areas involving bilateral cerebral white matter but also basal ganglia, brainstem, and cerebellar and cerebral cortex gray matter) may help to differentiate ADEM from the onset of a multiple sclerosis.…”

Section: Persistent Loss Of Consciousness: Approach In the Emergency Settingsmentioning

confidence: 99%

Management of Neurological Emergencies in Children: An Updated Overview

Mastrangelo

Baglioni

2021

Neuropediatrics

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Neurological emergencies account for about one-third of the highest severity codes attributed in emergency pediatric departments. About 75% of children with acute neurological symptoms presents with seizures, headache, or other paroxysmal events. Life-threatening conditions involve a minor proportion of patients (e.g., less than 15% of children with headache and less than 5% of children with febrile seizures). This review highlights updated insights about clinical features, diagnostic workup, and therapeutic management of pediatric neurological emergencies. Particularly, details will be provided about the most recent insights about headache, febrile seizures, status epilepticus, altered levels of consciousness, acute motor impairment, acute movement disorders, and functional disorders, as well as the role of diagnostic tools (e.g., neuroimaging, lumbar puncture, and electroencephalography), in the emergency setting. Moreover, the impact of the current novel coronavirus disease2019 (COVID-19) pandemic on the evaluation of pediatric neurologic emergencies will also be analyzed.

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