Acute disseminated encephalomyelitis after dengue

Diallo, A.; Dembele, Yacouba; Michaud, Céline; Jean, Maxime; Niang, Mohamadou; Meliani, P.; Yaya, Issifou; Permal, S.

doi:10.1016/j.idcr.2020.e00862

Cited by 5 publications

(1 citation statement)

References 10 publications

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“…ADEM is a neurological manifestation rarely described in association with dengue 2. AHEM is the most severe form of ADEM and is thought to be due to autoimmune cross reaction to the myelin antigens.…”

Section: Descriptionmentioning

confidence: 99%

Acute haemorrhagic encephalomyelitis following dengue infection

et al. 2022

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Section: Descriptionmentioning

confidence: 99%

Acute haemorrhagic encephalomyelitis following dengue infection

et al. 2022

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Dengue virus infection and neurological manifestations: an update

Fong,

Wong,

Tan

2023

Brain

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Dengue virus is a flavivirus transmitted by the mosquitoes, Aedes aegypti and Aedes albopictus. Dengue infection by all four serotypes (DEN 1 to 4) is endemic globally in regions with tropical and sub-tropical climates, with an estimated 100-400 million infections annually. Among those hospitalized, the mortality is about 1%. Neurological involvement has been reported to be about 5%. The spectrum of neurological manifestations spans both the peripheral and central nervous systems. These manifestations could possibly be categorised into those directly related to dengue infection, i.e. acute and chronic encephalitis, indirect complications leading to dengue encephalopathy, and post-infectious syndrome due to immune-mediated reactions, and manifestations with uncertain mechanisms such as acute transverse myelitis, acute cerebellitis, and myositis. The rising trend in global dengue incidence calls for attention to a more explicit definition of each neurological manifestation for more accurate epidemiological data. The actual global burden of dengue infection with neurological manifestation is essential for future planning and execution of strategies, especially in the development of effective antiviral and vaccines against the dengue virus. In this update, we discussed the recent findings of different spectrums of neurological manifestations in dengue infection and provided up-to-date antiviral and vaccine development and its challenges.

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Dengue Mimickers: Which Clinical Conditions Can Resemble Dengue Fever?

Farias,

Costa,

Bessa

et al. 2024

Rev. Soc. Bras. Med. Trop.

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Epidemics and outbreaks caused by the dengue virus pose risks to populations and have high mortality rates, causing burdens and economic costs worldwide. Brazil recently experienced an explosive increase in the number of dengue cases and fatalities. Dengue is an acute febrile illness that can progress to severe forms. It affects more than 100 countries, presenting ongoing challenges in Brazil and globally since its identification. Other conditions may be overlooked or mistaken for dengue. The most important differential diagnoses are other infectious diseases and rheumatological, hematological, gastroenterological, and neurological disorders. In this article, we discuss the primary differential diagnoses of dengue and offer a literature review highlighting the key clinical differences among clinicians. This review emphasizes the critical importance of differentiating dengue fever from infectious diseases such as meningococcemia and malaria and autoimmune and rheumatological conditions such as systemic lupus erythematosus to ensure timely and appropriate management.

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Acute disseminated encephalomyelitis after dengue

Cited by 5 publications

References 10 publications

Acute haemorrhagic encephalomyelitis following dengue infection

Acute haemorrhagic encephalomyelitis following dengue infection

Dengue virus infection and neurological manifestations: an update

Dengue Mimickers: Which Clinical Conditions Can Resemble Dengue Fever?

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