Acute Disseminated Encephalomyelitis following <i>Leptospira</i> Infection

Acute Disseminated Encephalomyelitis: Clinical and Pathogenesis Features

“…ADEM has also been reported after Legionella pneumophila infections [76], typhoid fever, and leptospirosis [77]. ADEM has been reported as a neurologic syndrome after malaria infection, and distinguishable from cerebral malaria.…”

The clinical spectrum and immunobiology of parainfectious neuromyelitis optica (Devic) syndromes

“…Of note, this phenomenon is widely missing in NMO [56]. The most frequent viral infections preceding ADEM are measles, VZV, rubella, mumps and influenza virus [57] while associations with bacterial agents are less frequently reported and involve streptococcus, legionella, typhus, borrelia and leptospirosis [58][59][60].…”

Acute Disseminated Encephalomyelitis after Leptospirosis infection

“…ADEM probably stems from an autoimmune process triggered by infection or immunization and often no causal factor is identified (1,2,3). The organisms most related to this pathology are the viruses and there are few cases of post-infection ADEM described in the world literature (3,4,5,6).…”