Acute effect of mercury toxicity on some enzymes in liver of teleost Sarotherodon mossambicus

Naidu, K. Akhilender; Ramamurthi, R.

doi:10.1016/0147-6513(84)90024-1

Cited by 16 publications

(10 citation statements)

References 16 publications

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“…In the present investigation the oxidative enzyme, SDH showed a reduction in its activity in all the osmoregulatory (gill and kidney) and non-osmoregulatory (liver, muscle and brain) tissues of the fish C. carpio, which indicates the suppression of oxidative metabolism in the fish exposed to ACTP [15]. As the SDH is the oxidative enzyme involved in Kreb's cycle, any disturbance in this enzyme activity will affect the Kreb's cycle.…”

Section: Discussionsupporting

confidence: 51%

Impact of Acute Lethal and Chronic Sublethal toxicity of Phorate on Succinate Dehydrogenase activity in the Fresh Water Fish Cyprinus carpio

Lakshmaiah

2016

Int J of Biomed & Adv Res

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The present study is aimed to investigate the acute and chronic toxicity stress of phorate, induced alterations in the activity levels of Succinate dehydrogenase (SDH), a vital enzyme of citric acid cycle that catalyses the reversible oxidation of succinate to fumarate. Freshwater fish Cyprinus carpio (C. carpio) were exposed to acute lethal toxicity (LC 50 /96 hours -0.71 ppm/l) of Phorate (ALTP) for one day and 4 days and chronic sublethal toxicity (one-tenth of the LC 50 /96 hours -0.071 ppm/l) of Phorate (CSTP) for 1, 7, 15 and 30 days. After the completion of stipulated exposure period the SDH enzyme activity levels were estimated in the vital organs of fish such as gill, liver, muscle, kidney and brain. The activity of SDH in all the organs of the fish exposed to phorate decreased at 1 and 4 days of exposure in acute toxicity in the order, day 1>4. The decrease was more at day 4 than at day 1. In the fish exposed to chronic toxicity of phorate (CTP), in the activity of SDH from day 1 to day 7 there was increase in the decrement but from day 7 to day 30 it was regressed in all the organs of the fish in the order, day 1>7<15<30. The differences in the SDH activity between controls and experimental were found to be statistically significant (P<0.05). The present study indicates the phorate induced alterations in the activities of carbohydrate metabolic enzyme caused significant metabolic effect on the physiological consequences.

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Section: Discussionsupporting

confidence: 51%

Impact of Acute Lethal and Chronic Sublethal toxicity of Phorate on Succinate Dehydrogenase activity in the Fresh Water Fish Cyprinus carpio

Lakshmaiah

2016

Int J of Biomed & Adv Res

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“…Other stress like various heavy metal contamination (Garg et al, 2009), cold (Haque et al, 2009) exercise (Driedzick & Hochachkka, 1979) or severe hypoxia (Heath & Pritchard, 1965) also cause rapid depletion of stored carbohydrate, primarily liver and muscle glycogen. According to Shastry & Rao (1984) and Naidu et al (1984) the decreases in the glycogen contents in the muscles and liver of the fish following exposure to heavy metals are species specific perhaps due to their metabolic differences and environmental concentration of heavy metals and duration to which the fishes are exposed. Diwan et al (1979 ) noticed that decrease in glycogen contents in different organ systems following exposure to industrial effluents (loaded with high concentration of Cd, Co, Cr, Pb, and Fe) were different in the same or different fishes.…”

Section: Discussionmentioning

confidence: 99%

Study of sodium arsenite induced biochemical changes on certain biomolecules of the freshwater catfish Clarias batrachus

Kumar

Banerjee

2012

Neotrop. ichthyol.

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Toxic impact of sublethal concentration (1 mg/L; 5% of 96h LC 50 value) of sodium arsenite (NaAsO 2 ) on certain biomolecules (proteins, nucleic acids, lipids, and glycogen) of five tissue components (muscles, liver, brain, skin, and gills) of the freshwater catfish Clarias batrachus was analysed. The important toxic manifestations include marked decrease in the concentration of proteins (21.72-45.42% in muscles; 3.42-53.94% in liver; 15.39-45.42% in brain; 15.40-4.00% in skin and 11.35-64.13% in gills), .01% in gills), .93% in skin and 21.47-44.38% in gills) and glycogen (24.00-51.72% in muscles; 49.11-72.45% in liver; 11.49-26.03% in brain; 26.13-38.05% in skin and 17.80-37.97% in gills). Excepting liver where the lipid content increases (15.82-24.13%), the fat content also showed depletion in their concentration (10.40-29.83% in muscles; 8.30-34.45% in brain; 8.94-31.47% in skin and 12.75-28.86% in gills), in the rest of the organ systems.Foi analisado o impacto tóxico da concentração subletal (1 mg/L; 5% do valor de LC50 de 96h) do arsenito de sódio (NaAsO2) sobre certas biomoléculas (proteinas, ácidos nucleicos, lipídios e glicogênio) de cinco tecidos (músculos, fígado, cérebro, pele e brânquias) do bagre Clarias batrachus. As manifestações tóxicas importantes incluiram o decréscimo acentuado na concentração de proteinas (21,72-45,42% nos músculos; 3,42-53,94% no fígado; 15,39-45,42% no cérebro; 15,40-4,00% na pele e 11,35-64,13% nas brânquias), DNA (0,55-22,95% nos músculos; 8,33-14,06% no fígado; 5,30-18,40% no cérebro; 13,57-52,80% na pele e 12,38-31,01% nas brânquias), RNA (42,[68][69][70][71][72][73][74][75][76]16% nos músculos; 10,75% no fígado; 5,05% no cérebro; 7,93% na pele e 21,47-44,38% nas brânquias) e glicogênio (24,00-51,72% nos músculos; 49,11-72,45% no fígado; 11,49-26,03% no cérebro; 26,13-38,05% na pele e 17,80-37,97% nas brânquias). Excetuando o fígado onde o conteúdo de lipídeos aumentou (15,82-24,13%), houve uma depleção na concentração de lipídeos no restante dos sistemas orgânicos (10,40-29,83% nos músculos; 8,30-34,45% no cérebro; 8,94-31,47% na pele e 12,75-28,86% nas brânquias).Key words: Glycogen, Lipids, Nucleic acids, Proteins, Toxicity.Banaras Hindu University, Eco-physiology Unit, Department of Zoology, Varanasi-221 005, India. randhir18bhu@gmail.com (RK), tkbzool@yahoo.co.in (TKB) IntroductionThere has been a continuous and alarming influx of arsenic to aquatic environment worldwide from both naturally occurring and anthropogenic sources (Goering et al., 1999). More than one hundred million people are at high risk of elevated arsenic exposure, mainly via drinking water, as well as by the air born metalloid in the areas with coal burning and industrial emissions. Consumption of the arsenic contaminated fishes collected from the polluted waters might also contribute to bioaccumulation of arsenic in human beings. Hence it is of immense importance to know the arsenic induced damages in the different organ systems of fishes used for human consumption. In an effort to achieve t...

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“…Heavy metals are considered natural trace components of the aquatic environment, but their ground levels in the environment have been increased, especially at the industrial and agricultural fields, as well as mining activities (Langston, 1990;Bryan & Langston, 1992). Many studies were carried out on different fish species and revealed that both essential (Cu & Zn) and nonessential (Cd & Pb) metals cause toxic effects in fish through disturbing the physiological activities (Naidu et al,1984 ;Grobler et al .,1989;Kraak et al, 1994^ biochemical processes (Dange,1986 ;Canli, 1996 ;Soliman et al, 2004), reproduction and growth (Collvin, 1985 ;Weis & Weis, …”

Section: Introductionmentioning

confidence: 99%

Impact of Certain Heavy Metals on the Gill and Liver of the Nile Tilapia (Oreochromis Niloticus)

Gaber

2007

Egypt. J. of Aquatic Biolo. and Fish.

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T he effect of the heavy metals Cu, Zn, Cd and Pb on the gill and liver tissues of the Nile tilapia, Oreochromis niloticus was examined in the laboratory. One hundred and fifty adult fish were divided into five groups (control, copper, zinc, cadmium and lead) each group containing 30 fish. They were continuously exposed to sub-lethal concentration of each metal (lmg/L) for a period of 10 days. From each group, the gills and liver of six fish were removed after 10 days and the remaining fish were transferred to tap water for : a recovery period (21days). The tissue samples of gills and liver of both treated and recovery fish were dissected for histological examination. The results showed that the extent of distortion of the gills and liver was more pronounced in the fish group that were exposed to Cd&Pb.

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Acute effect of mercury toxicity on some enzymes in liver of teleost Sarotherodon mossambicus

Cited by 16 publications

References 16 publications

Impact of Acute Lethal and Chronic Sublethal toxicity of Phorate on Succinate Dehydrogenase activity in the Fresh Water Fish Cyprinus carpio

Impact of Acute Lethal and Chronic Sublethal toxicity of Phorate on Succinate Dehydrogenase activity in the Fresh Water Fish Cyprinus carpio

Study of sodium arsenite induced biochemical changes on certain biomolecules of the freshwater catfish Clarias batrachus

Impact of Certain Heavy Metals on the Gill and Liver of the Nile Tilapia (Oreochromis Niloticus)

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