Acute Effect of Particulate Matter Pollution on Hospital Admissions for Stroke among Patients with type 2 Diabetes in Beijing, China, from 2014 to 2018

Abstract

Background: The health effect of particulate matter pollution on stroke has been widely examined; however, the effect among patients with comorbid type 2 diabetes (T2D) in developing countries has remained largely unknown.Methods: A time-series study was conducted to investigate the short-term effect of fine particulate matter (PM2.5) and inhalable particulate matter (PM10) on hospital admissions for stroke among patients with T2D in Beijing, China, from 2014 to 2018. An over-dispersed Poisson generalized additive model was employed to adjust for important covariates, such as weather conditions and long-term and seasonal trends. Results: A total of 159,298 (58% male) hospital admissions for stroke were reported. Linear exposure-response curves were observed for PM2.5 and PM10 in relation to stroke admissions among T2D patients. A 10 μg/m3 increase in the four-day moving average of PM2.5 and PM10 was associated with 0.14% (95% confidence interval [CI]: 0.05%-0.23%) and 0.14% (95% CI: 0.06%-0.22%) incremental increases in stroke admissions among T2D patients, respectively. A 10 μg/m3 increase in PM2.5 in the two-day moving average corresponded to a 0.72% (95% CI: 0.02%-1.42%) incremental increase in hemorrhagic stroke, and a 10 μg/m3 increase in PM10 in the four-day moving average corresponded to a 0.14% (95% CI: 0.06%-0.22%) incremental increase in ischemic stroke. Conclusions: High particulate matter might be a risk factor for stroke among patients with T2D. PM2.5 and PM10 have a linear exposure-response relationship with stroke among T2D patients. The study provided evidence of the risk of comorbid T2D and stroke due to particulate matter pollution.

Acute Effects of Metrological Factors on Cerebrovascular Diseases among Type2 Diabetes Patients: case crossover evidence from Beijing, China

“…Third, since the date of diagnostic is not available, it cannot be differentiated between the accurate occurrence of stroke and T2D. Fourth, the generalizability of our results might be limited as the study collected data from one highly polluted city and only included T2D [28][29][30][31][32][33][34][35][36].…”

The Short‐Term Effects and Burden of Ambient Air Pollution on Hospitalization for Type 2 Diabetes: Time‐Stratified Case‐Crossover Evidence From Sichuan, China

“…Around the world, almost 99% people are breathing the air that are above the limits of World Health Organization (WHO, 2022). In recent years, various studies have investigated the associations between short‐term exposure to ambient air pollution and T2DM incidence and burden (Liu et al., 2013, 2021a; Rajagopalan & Brook, 2012). Globally, 3.2 million cases of diabetes mellitus were linked with ambient air particle matter (PM), rendering to 8.3 million disability‐adjusted life‐years (Benjamin et al., 2018).…”