Acute effects of albumin infusion on blood volume and renal function in premature infants with respiratory distress syndrome

Renal impact of fluid management with colloids: a comparative review

“…The fractionate is pasteurized to inactivate infectious agents. Albumin infusion increases blood volume, renal blood flow and glomerular filtration rate [120][121][122].…”

Use and misuse of albumin infusions in neonatal care

“…Indeed, in premature infants with respiratory distress syndrome (RDS), an albumin infusion increased the colloid osmotic pressure and the creatinine clearance rate [19]. In a study [13] of ten babies, who had albumin levels less than or equal to 30 g/l but were normotensive, administration of 5 ml/kg of 20% salt-poor albumin as part of the maintenance¯uids was associated with a signi®cant increase in albumin level from a mean of 27 g/l to 32 g/l and a doubling of urine output; the babies lost approximately 40 g in weight over the study period.…”

Effects of Human Albumin Infusion on Transepidermal Water Loss in Newborn Infants

“…Therefore, the plasma albumin concentration will only increase moderately during infusion, and the increase in plasma volume will also probably be small. In another study [20] a much more rapid and massive infusion of human albu min in newborn infants (1 g/kg in 10 min) increased the plasma volume by about 30%, and simultaneously the arterial blood pres sure rose. In the present investigation the arterial blood pressure did not increase dur ing the infusion.…”