Acute Effects of Local Ischemic Hypoxia and Systemic Hypoxemia on Neuromuscular and Cognitive Function

Rivera, Paola M.; Proppe, Christopher E.; Beltran, Esther; Hill, Ethan C.

doi:10.1089/ham.2021.0096

Cited by 2 publications

(2 citation statements)

References 34 publications

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“…2B). This is again indicative of an inability to fully recover during the 30 s of interset rest, regardless of cuff pressure, creating at least a quasi-hypoxic environment to hypothetically drive positive, exercise-induced adaptations (57,58). An exciting future direction includes the continued evaluation of positive adaptations resulting from BFR applied only during rest phases.…”

Section: Discussionmentioning

confidence: 99%

Effects of Sex and Cuff Pressure on Physiological Responses during Blood Flow Restriction Resistance Exercise in Young Adults

Gray

Cuomo

Proppe

et al. 2022

Medicine &Amp; Science in Sports &Amp; Exercise

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PurposeThe purpose of this study was to examine the physiological responses resulting from an acute blood flow restriction resistance exercise bout with two different cuff pressures in young, healthy men and women.MethodsThirty adults (18–30 yr) completed a bilateral leg extension blood flow restriction bout consisting of four sets (30–15–15–15 repetitions), with cuffs applied at pressures corresponding to 40% and 60% of the minimum arterial occlusion pressure (AOP) needed to completely collapse the femoral arteries. During each of these conditions (40% and 60% AOP), physiological measures of near-infrared spectroscopy (NIRS) and EMG amplitude (EMG AMP) were collected from the dominant or nondominant vastus lateralis. After each set, ratings of perceived exertion (RPE) were collected, whereas only at baseline and at the end of the bout, mean arterial pressure (MAP) was assessed. Separate mixed-factorial ANOVA models were used to examine mean differences in the change in EMG AMP and NIRS parameters during each set. The absolute RPE and MAP values were also examined with separate ANOVAs. A P value ≤0.05 was considered statistically significant.ResultsRegardless of sex or cuff pressure, the change in EMG AMP was lower in set 1 (14.8%) compared with the remaining sets (22.6%–27.0%). The 40% AOP condition elicited the greatest changes in oxy[heme] and deoxy[heme], while also providing lower RPEs. For MAP, there was an effect for time such that MAP increased from preexercise (87.5 ± 4.3 mm Hg) to postexercise (104.5 ± 4.1 mm Hg).ConclusionsThe major findings suggested that the 40% AOP condition permitted the greatest amount of recovery during the interset rest. In addition, there did not seem to be any meaningful sex-related difference in this sample of young healthy adults.

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Section: Discussionmentioning

confidence: 99%

Effects of Sex and Cuff Pressure on Physiological Responses during Blood Flow Restriction Resistance Exercise in Young Adults

Gray

Cuomo

Proppe

et al. 2022

Medicine &Amp; Science in Sports &Amp; Exercise

Self Cite

View full text Add to dashboard Cite

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“…Persistent hypoxemia in COPD patients leads to cerebral white matter lesions, similar to those observed in studies focusing on elderly individuals with depression. Additionally, other researchers suggest that sustained hypoxemia impairs cognitive function, and one of the sequelae is depression, positing hypoxemia as a potential factor in inducing depression in patients [28,29].…”

Section: Hypoxemiamentioning

confidence: 99%

Research Progress on Influencing Factors, Mechanisms, and Therapeutic Regimens of Adverse Emotions in COPD Patients

Xiao,

2023

IJCEMR

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Chronic obstructive pulmonary disease (COPD) is a serious respiratory system disease in China and even the world, which seriously affects patients' health and quality of life. In addition to COPD symptoms, the accompanying anxiety, depression, and other adverse emotions have gradually attracted widespread attention. Based on the summary of previous literature, this article summarizes the influencing factors of adverse emotions in COPD patients, including smoking, chronic pain, activity limitation, drug effect, gender, fatigue, etc. Clinical treatment can be taken through continuous and close observation of the influencing factors of adverse emotions, and timely and effective intervention measures can be taken for high-risk groups. At present, the exact pathogenesis of anxiety and depression in COPD patients is still unclear. It involves multiple complex pathophysiological factors such as hypoxemia and chronic inflammation, which may also include behavioral factors such as active smoking and tobacco addiction, as well as other factors such as social isolation, complications, declined physical function, and frequent re-hospitalization. This study summarizes several mechanisms such as hyperventilation, carbon dioxide retention, hypoxemia, inflammation, immune regulation, cognitive behaviors, and sleep disorders so as to determine the possible mechanisms of anxiety, depression, and other adverse emotions in COPD patients and to assist the clinical search for effective therapeutic targets. Finally, this article summarizes the treatment progress of adverse emotions in COPD patients mainly through antipsychotics and TCM therapy, individualized breathing intervention, and cognitive behavioral therapy.

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Acute Effects of Local Ischemic Hypoxia and Systemic Hypoxemia on Neuromuscular and Cognitive Function

Cited by 2 publications

References 34 publications

Effects of Sex and Cuff Pressure on Physiological Responses during Blood Flow Restriction Resistance Exercise in Young Adults

Effects of Sex and Cuff Pressure on Physiological Responses during Blood Flow Restriction Resistance Exercise in Young Adults

Research Progress on Influencing Factors, Mechanisms, and Therapeutic Regimens of Adverse Emotions in COPD Patients

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