Acute Effects of Passion Fruit Juice Supplementation on Cardiac Autonomic Function and Blood Glucose in Healthy Subjects

Abstract

Ascorbic acid supplementation provides beneficial effects on enhancing cardiac autonomic function in patients with heart failure. Ascorbic acid also reduces blood sugar levels and enhances insulin activity, and encourages cardiac autonomic function. Passion fruit is rich in ascorbic acid and potential antioxidants. This study aimed to evaluate the acute effects of passion fruit juice (PFJ) supplementation primarily on cardiac autonomic function and secondary on blood glucose in healthy subjects. A randomized cross-over trial was conducted in 14 healthy subjects aged 21.29±0.73 years. Subjects were supplemented with either 50% PFJ, or glucose and fructose solution as a placebo (PLA) at 3.5 mL/kg body mass with a 1-week washout between treatments in a single-dose design. Short-term heart rate variability and blood glucose levels were evaluated prior to supplementation (T0) and following supplementation for 30, 60, 90, and 120 min (T30, T60, T90, and T120, respectively). Indexes of cardiac autonomic function at T30, including high frequency power (P=0.03) and total power (P=0.01), were significantly higher and the ratio of low frequency/high frequency power was significantly lower (P=0.01) in the PFJ group compared to the PLA group. Blood glucose levels significantly increased at T30 in both PLA (P=0.00) and PFJ (P=0.00) groups. However, there were no significant differences between groups. A single administration of PFJ enhanced cardiac autonomic function through augmentation of parasympathetic activity, although it did not attenuate postprandial hyperglycemia. PFJ may be potentially recognized as beverage able to prevent cardiovascular disease.

Comparison of the Effects of High Pressure Processing, Pasteurization and High Temperature Short Time on the Physicochemical Attributes, Nutritional Quality, Aroma Profile and Sensory Characteristics of Passion Fruit Purée

“…Moreover, significant changes in nutritional and functional compounds were usually reported for fruit products after thermal PT. For example, vitamin C is the relevant nutrient in yellow passion fruit within a range of 0.16–0.20 g/kg [ 11 ], which is thermoplastic and easily degraded after thermal PT. It was also reported that vitamin C in kiwifruit was significantly reduced by 38.39% after thermal treatment (110 °C/8.6 s) [ 12 ].…”

Flavonoids Accumulation in Fruit Peel and Expression Profiling of Related Genes in Purple (Passiflora edulis f. edulis) and Yellow (Passiflora edulis f. flavicarpa) Passion Fruits

“…It is also called passion flower or egg fruit because it contains apple, guava, banana, strawberry, mango, pineapple, and 130 other kinds of fruit aroma [2,3]. The peel and pulp of passion fruit have many biological functions, such as controlling blood sugar [4], anti-hypertension [5,6], anti-inflammation and reducing fat [7], protecting liver and kidney [8], and regulating cardiac autonomic nerve functions [9]. In addition, passion fruit peel powder can be used as food raw material when added to baking products [10,11].…”

Acute Effect of Riceberry Waffle Intake on Postprandial Glycemic Response in Healthy Subjects

“…However, recently some clinical studies have been published in the literature that use only 10 participants for measuring postprandial glycemic response [ 59 , 60 , 61 , 62 ]. Additionally, due to its convenience in application for the participants, a glucometer was used in most of these studies [ 28 , 29 , 30 , 31 , 32 ]. In addition, it was reported that the use of a glucometer for monitoring the postprandial blood glucose level has an acceptable sensitivity [ 63 ].…”

“…This study was a single-blind controlled study. The study consisted of three experimental trials (two test meals and one reference) carried out on three different occasions in accordance with the literature [ 28 , 29 , 30 , 31 , 32 ]. We allowed a one-week wash out period between each visit.…”