Acute effects of pistachio consumption on glucose and insulin, satiety hormones and endothelial function in the metabolic syndrome

Kendall, Cyril W.C.; West, Sheila G.; Augustin, Livia S. A.; Esfahani, Amin; Vidgen, Edward; Bashyam, Balachandran; Sauder, Katherine A.; Campbell, Janice; Chiavaroli, Laura; Jenkins, Alexandra L.; Jenkins, David

doi:10.1038/ejcn.2013.275

Cited by 59 publications

(76 citation statements)

References 40 publications

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“…Randomized clinical trials found that patients consuming a pistachio-supplemented diet show significantly decreased postprandial glycemia, insulin, fasting glucose, and HOMA-IR, and increased GLP-1 [12,13]. Based on these considerations, nuts may potentially improve glycemic control and reduce inflammatory factors in diabetic patients.…”

Section: Introductionmentioning

confidence: 99%

“…Based on these considerations, nuts may potentially improve glycemic control and reduce inflammatory factors in diabetic patients. However, there is little evidence for the efficacy of pistachio on glycemic control of diabetic patients [12][13][14]. Therefore, this study was designed to investigate the effectiveness of pistachio consumption on blood glucose of type 2 diabetic patients in a crossover clinical trial.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Pistachio Nut Supplementation on Blood Glucose in Patients with Type 2 Diabetes: A Randomized Crossover Trial

et al. 2014

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■ AbstractBACKGROUND: Diabetes is a chronic, potentially debilitating, and often fatal disease. Dietary strategies to reduce postprandial glycemia are important in the prevention and treatment of diabetes. Nuts are rich in mono-and polyunsaturated fatty acids, which may reduce hyperglycemia and improve metabolism. OBJECTIVES: To evaluate the effectiveness of pistachio nut supplementation on glycemic and inflammatory measures in patients with type 2 diabetes. METHODS: In this double-blind, randomized, placebocontrolled, crossover trial, 48 diabetic patients were equally assigned to groups A and B. Patients in group A received a snack of 25 g pistachio nuts twice a day for 12 weeks and group B received a control meal without nuts. After 12 weeks of intervention, the patients had an 8-week washout. Then the groups were displaced, and group B received the same amount of pistachios for 12 weeks. RESULTS: With respect to the total change in variables over both phases, there was a marked decrease in HbA1c (-0.4%) and fasting blood glucose (FBG) concentrations (-16 mg/dl) in the pistachio group compared with the control group (p ≤ 0.001 for both). There was no overall significant change in BMI, blood pressure, HOMA-IR, and C-reactive protein (CRP) concentrations. Analysis of the two phases separately showed a decrease in FBG by 14 mg/dl and in HbA1c by 0.45% in the treatment group (A) after 12 weeks, while no significant differences were seen in group B (control group). In the second phase, FBG decreased from 151.36 ± 39.22 to 137.28 ± 28.65 mg/dl (-14 mg/dl) and HbA1c decreased from 7.42 ± 0.97 to 7.15 ± 0.68 mg/dl (-0.28%, p = 0.013 and p = 0.033, respectively) in the pistachio group (B). Pistachio consumption reduced systolic blood pressure (p = 0.007), BMI (p = 0.011), and CRP (p = 0.002) in patients from the treatment groups, but not insulin resistance. CONCLUSIONS: Dietary consumption of pistachio nuts as a snack has beneficial effects on glycemic control, blood pressure, obesity, and inflammation markers in diabetic patients.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of Pistachio Nut Supplementation on Blood Glucose in Patients with Type 2 Diabetes: A Randomized Crossover Trial

et al. 2014

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“…[76], yemek sonrası glukoz seviyelerini incelediği çalışmasında glisemik indeksi yüksek pirinç ve makarna gibi yaygın karbonhidrat içeren gıdalara antepfıstığını eklemiş ve tüketen kişilerin kan glukoz seviyesinin önemli bir oranda azaldığını tespit etmişlerdir. Ayrıca, antepfıstığı daha uzun süre tokluk hissinin sürdürülmesine ve yemek sonrası kan glikoz konsantrasyonlarının düşürülmesine katkı sağlayan düşük glisemik indekse sahip bir besin maddesidir [77,78]. Düşük glisemik indekse sahip olan antepfıstığı potansiyel olarak diyabet riskini azaltmaktadır [76,77].…”

Section: İnsan Sağliği Açisindan Antepfistiğinin öNemi̇unclassified

“…Ayrıca, antepfıstığı daha uzun süre tokluk hissinin sürdürülmesine ve yemek sonrası kan glikoz konsantrasyonlarının düşürülmesine katkı sağlayan düşük glisemik indekse sahip bir besin maddesidir [77,78]. Düşük glisemik indekse sahip olan antepfıstığı potansiyel olarak diyabet riskini azaltmaktadır [76,77]. Tip 2 diyabete sahip yetişkinlerin diyetinde günlük enerjinin %20'sini antepfıstığından sağlayan grupla diyetinde antepfıstığı bulunmayan (kontrol) grup karşılaştırıldığında daha düşük toplam kolesterol, trigliserid ve fruktozamin tespit edilmiştir.…”

Section: İnsan Sağliği Açisindan Antepfistiğinin öNemi̇unclassified

“…Kendall ve ark. [77], 20 kişi üzerinde gerçekleştirdiği çalışmasında her gruba uygun karbonhidrat içeren gıdalar verildiğinde beyaz ekmek tüketimi ardından yemek sonrası glukoz seviyesini en yüksek belirlemişler ve antepfıstığı tüketimi ardından yemek sonrası glukoz seviyesinin azaldığını bildirmişlerdir.…”

Section: İnsan Sağliği Açisindan Antepfistiğinin öNemi̇unclassified

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Antepfıstığı (Pistacia vera L.) ve İnsan Sağlığı Üzerine Etkileri

Çağlar¹,

Tomar²,

Vatansever³

et al. 2017

Akademik Gıda

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Pistachio (Pistacia vera L.) and Its Effects on Human HealthABSTRACT Turkey, especially Southeastern Anatolian Region, has an important place in the world ranking as well as an economic value in terms of pistachio production. Pistachios, which are from nuts with hard shells, have positive effects on health. Pistachios have rich nutritional content in terms of protein, fat and fatty acids, fiber, vitamins and minerals. As a rich source of phenolic compounds, pistachios take attention with a high antioxidant activity. Various researchers have reported that pistachio consumption may have beneficial effects on hypertension, cancer, diabetes and cardiovascular diseases. In this present study, the place and the importance of pistachios in human nutrition and health are reviewed.

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Nut-enriched bread is an effective and acceptable vehicle to improve regular nut consumption

et al. 2015

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Acute effects of pistachio consumption on glucose and insulin, satiety hormones and endothelial function in the metabolic syndrome

Abstract: Compared with white bread, pistachio consumption reduced postprandial glycemia, increased glucagon-like-peptide levels and may have insulin-sparing properties. These effects could be beneficial for individuals with diabetes and metabolic syndrome.

Cited by 59 publications

References 40 publications

Effects of Pistachio Nut Supplementation on Blood Glucose in Patients with Type 2 Diabetes: A Randomized Crossover Trial

Effects of Pistachio Nut Supplementation on Blood Glucose in Patients with Type 2 Diabetes: A Randomized Crossover Trial

Antepfıstığı (Pistacia vera L.) ve İnsan Sağlığı Üzerine Etkileri

Nut-enriched bread is an effective and acceptable vehicle to improve regular nut consumption

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