Acute exacerbation of staphylococcal catarrhal infiltration associated with treatment for Pseudomonas aeruginosa keratitis

Bang, Seung Pil; Jun, Jong Hwa

doi:10.1097/md.0000000000010753

Cited by 3 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, the ophthalmologist at the local hospital insisted on acyclovir and cyclosporine treatment. In addition, the patient developed a rapidly aggravated peripheral corneal infiltration, 9 which may have also led to the suspicion of secondary autoimmune-related keratitis caused by viral infection; this might have supported the cyclosporine treatment prescribed by the local hospital. After the patient was admitted to our hospital, we strongly suspected that he had multimicrobial keratitis with Acanthamoeba infection, given the signs of radioneuritis and ineffectiveness of the previous antiviral treatment regimen, as well as his long history of wearing Ortho-K contact lenses.…”

Section: Discussionmentioning

confidence: 94%

Clinical diagnosis and treatment of rare painless keratitis caused by three pathogens: clinical practice and experiential discussion

Sun

Wang

et al. 2020

J Int Med Res

View full text Add to dashboard Cite

There have been numerous reports regarding the occurrence of keratitis in patients with soft contact lenses, but few reports in patients with rigid gas permeable contact lenses. To the best of our knowledge, the occurrence of infection associated with three species of pathogens has never been reported. Here, we describe a patient who exhibited refractory painless keratitis caused by three pathogens (Staphylococcus epidermidis, Acanthamoeba, and herpes simplex virus) and summarize similar reports published at multiple centers worldwide, with the aim of providing guidance for clinicians who might encounter mixed-type corneal infections. We describe the results of many ophthalmologic and laboratory investigations, which guided our treatment selection. We achieved good treatment efficacy, such that the patient exhibited a corrected visual acuity of 20/20 in the affected eye after a series of treatments, including curettage of ulcer lesions. Corneal infections caused by multiple pathogens are challenging in clinical practice. This summary of our experience in patient diagnosis and treatment can help clinicians to achieve a favorable prognosis in treatment of future patients.

show abstract

Section: Discussionmentioning

confidence: 94%