Acute Exposure Guideline Levels for Selected Airborne Chemicals

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doi:10.17226/13377

Cited by 3 publications

(1 citation statement)

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“…Extremely high concentrations can cause death by displacement of oxygen from the lungs. Case studies also reveal that serious brain damage and underdeveloped organs can occur in fetuses in case of high single exposures during the week 27 or 30 of pregnancy" [26]. Sugie et al [27] reported "three cases of sudden death due to inhalation of portable cooking stove fuel (case 1), cigarette lighter fuel (case 2), and liquefied petroleum gas (LPG) (case 3).…”

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confidence: 99%

Tumour Necrotic Factor Alpha level and Some Biochemical Parameters as a Measure of Health Risks Due to Exposure to Liquefied Petroleum Gas on Vendors in Calabar, Nigeria

Abara

Nsonwu-Anyanwu

Etukudoh

et al. 2022

IJTDH

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Background: The human body is constantly exposed to chemicals and other substances injurious to health from the environments, foods etc. These substances are taken into the body either consciously or unconsciously through the mouth, nose, and skin which often lead to oxidative stress, gene mutation, direct injury on cells and tissue, alteration of immune system etc, resulting in cancer development and other chronic and acute health challenges and death. This study is aimed at assessing the health risks due to chronic exposure to non-combusted Liquefied Petroleum Gas (LPG) and appraising the potential inflammatory and liver problem among its vendors who did not wear Personal Protective Equipments (PPE). Methods: Forty-one apparently healthy Liquefied Petroleum Gas sellers and Forty-one apparently healthy non Liquefied Petroleum Gas sellers/user (control), aged 18 to 50 years were recruited for this study. The Body Mass Index (BMI) was determined by taking the ratio of weights in Kg to the square of heights in meters. Tumor Necrosis Factor Alpha (TNF-α) was estimated by Enzyme Linked Immunosorbent Assay (ELISA), 2-butanol was estimated using High Performance Liquid Chromatography (HPLC), ALT and AST were estimated using Colorimetric method. Data were analyzed using Student’s t-test and Pearson’s correlation at p<0.05. Results: From the results obtained, AST, ALT and BMI did not show significant variation but TNF-α and 2-butanol showed a significant variation compared to control. TNF-α and 2-butanol showed a significant positive correlation among the exposed group. The duration of exposure does not appear to cause a significant difference in the levels of the biochemical parameters. Conclusion: This study therefore showed that exposure to Liquefied Petroleum Gas has no effect on anthropometric and liver parameter but appears to cause significant elevation of TNF-α and 2-butanol, meaning that sellers may be predisposed to inflammation. It is therefore recommended that vendors of Liquefied Petroleum Gas (LPG) always wear their PPE to avoid deleterious effect on their health.

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Section: Introductionmentioning

confidence: 99%

Tumour Necrotic Factor Alpha level and Some Biochemical Parameters as a Measure of Health Risks Due to Exposure to Liquefied Petroleum Gas on Vendors in Calabar, Nigeria

Abara

Nsonwu-Anyanwu

Etukudoh

et al. 2022

IJTDH

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Role of defect engineering in revealing the electronic and sensing applications of Janus WSSe monolayer

2023

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Release of Microplastics from Reusable Kitchen Plasticware and Generation of Thermal Potential Toxic Degradation Products in the Oven

et al. 2022

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Plastics are one of the most important technical materials at present, yet they are associated with a whole series of environmental problems such as micro-and nanoplastics or their plasticizers, which have become increasingly relevant in recent years. While there are many studies that focus on microplastics (MPs) introduced into the human body through commercially produced food, there are nearly none that consider the MPs we ingest through homemade food made with plastic kitchen utensils such as mixing bowls. To investigate this, samples were obtained by exposing different plastic bowls made of acrylonitrile–butadiene–styrene (ABS), polypropylene (PP), melamine, polyethylene (PE), polystyrene (PS), and styrene–acrylonitrile (SAN), to mechanical stress and then analyzed via infrared spectroscopy. This not only raises the question of whether microplastics are incorporated into foods but also the extent to which the degradation products produced by thermal stress in an oven could play a toxicological role. Degradation products were generated by pyrolysis and analyzed afterwards using gas chromatography mass spectrometry. There were differences in the number of microplastic particles abraded by the different types of plastic, with the most consisting of melamine (898 particles) and the least consisting of low-density polyethylene (331 particles). There were also differences in the number and relevance of the thermal degradation products for the different plastics, so that a human toxicological assessment would have to be evaluated in further work.

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Acute Exposure Guideline Levels for Selected Airborne Chemicals

Cited by 3 publications

References 161 publications

Tumour Necrotic Factor Alpha level and Some Biochemical Parameters as a Measure of Health Risks Due to Exposure to Liquefied Petroleum Gas on Vendors in Calabar, Nigeria

Tumour Necrotic Factor Alpha level and Some Biochemical Parameters as a Measure of Health Risks Due to Exposure to Liquefied Petroleum Gas on Vendors in Calabar, Nigeria

Role of defect engineering in revealing the electronic and sensing applications of Janus WSSe monolayer

Release of Microplastics from Reusable Kitchen Plasticware and Generation of Thermal Potential Toxic Degradation Products in the Oven

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