Acute exposure of a glyphosate-based herbicide affects the gills and liver of the Neotropical fish, Piaractus mesopotamicus

Shiogiri, Natália Sayuri; Paulino, Marcelo Gustavo; Carraschi, Silvia Patrícia; Baraldi, Flávia G.; Cruz, Claudinei da; Fernandes, Marisa Narciso

doi:10.1016/j.etap.2012.05.007

Cited by 104 publications

(46 citation statements)

References 30 publications

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“…2012), congestions of sinusoids (Langiano & Martinez. 2008;Gawish, Issa, & Ali, 2011;Shiogiri et al, 2012), necrosis (Rahman, Hossain, & Mollah, 2002;Gu imaraes, Silva de Assis, & Boegera, 2007;Velmu rugan, Selvanayagam, Cengiz, & Unlu, 2009) and hemorrhages (Rodrigues & Fanta, 1998;Langiano & Martinez. 2008) in livers of many fish species.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Korkmaz¹,

DONMEZ²

2017

Turk. J. Fish. Aquat. Sci.

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Section: Discussionmentioning

confidence: 99%

Untitled

Korkmaz¹,

DONMEZ²

2017

Turk. J. Fish. Aquat. Sci.

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“…During the last decade, inadequate use of the environment for increasing agricultural productivity by intense pesticide use has significantly contributed to water contamination (Shiogiri et al 2012). Fish show changes in metabolic and enzymatic parameters as a consequence of pesticide-induced toxicity (Fatima et al 2007).…”

Section: Introductionmentioning

confidence: 99%

Commercial formulation containing 2,4-D affects biochemical parameters and morphological indices of silver catfish exposed for 90 days

Menezes

Fonseca

Leitemperger

et al. 2014

Fish Physiol Biochem

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The objective of this study was to verify whether a commercial formulation of 2,4 dichlorophenoxyacetic acid [2,4-D dimethylamine salt (DMA)] affects the growth and biochemical parameters of silver catfish (Rhamdia quelen) after 90 days of exposure. The fish exposed to 0.5 or 2.0 mg/L of DMA presented exhibited decreased growth parameters. Glucose was reduced in the mucus layer at both concentrations, and the total protein level was increased at the highest concentration tested. Fish exposed to DMA showed reduced liver and kidney glycogen at both concentrations tested, while in the muscle, glycogen was reduced only at 2.0 mg/L. Glucose was increased in the liver and decreased in the muscle and kidney at both concentrations and was not altered in the plasma. Lactate was increased in all the tissues and decreased in the plasma. Protein levels were reduced in the liver and plasma at both concentrations, while in the muscle, it was decreased at a concentration of 2.0 mg/L. Levels of thiobarbituric acid-reactive substances were reduced in the liver and increased in the muscle at both concentrations and did not change in the brain. DMA increased catalase activity in the liver at both concentrations tested. The present study demonstrates the effects of long-term exposure to DMA. Some parameters could be used as toxicity indicators to identify the presence of DMA in an aquatic environment.

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“…Cytotoxicity by oxidative stress by Roundup R has been shown by transcriptomic profiling in carp and zebrafish (Uren Webster and Santos, 2015;Sulukan et al, 2017). Acute toxicity, harmful physiological effects including hepatotoxicity, neurotoxicity, deteriorated sperm counts, early life stage development and DNA-damaging effects have been reported for numerous other fish species as well for sublethal exposures to Roundup R products including Roundup Original R , Roundup Transorb R and Roundup WG R , Garlon R , and other glyphosate-based herbicides (Soso et al, 2007;Cavalcante et al, 2008;Guilherme et al, 2010Guilherme et al, , 2014aModesto and Martinez, 2010;Shiogiri et al, 2012;Ghisi and Cestari, 2013;Nwani et al, 2013;Marques et al, 2014;Moreno et al, 2014;Navarro and Martinez, 2014;Richard et al, 2014;Sinhorin et al, 2014;Braz-Mota et al, 2015;Menéndez-Helman et al, 2015;Li et al, 2016;de Moura et al, 2017;Sánchez et al, 2017;Gonçalves et al, 2018;Zebral et al, 2018) or POEA (Yusof et al, 2014). Roundup R was found to disrupt 17β-estradiol and reduce glutathione concentration in the liver of the endangered fish species delta smelt (Hypomesus transpacificus) upon 6 h of exposure at levels corresponding to 78 µg/l glyphosate concentrations and above (Jin et al, 2018).…”

Section: Registration Of Glyphosate In the European Unionmentioning

confidence: 99%