Acute exposure to a quinalphos containing insecticide (convoy) causes genetic damage and nuclear changes in peripheral erythrocytes of silver barb, Barbonymus gonionotus

Sadiqul, Islam M.; Ferdous, Zannatul; Nannu, Md. Tanvir Ahmed; Mostakim, Golam Mohammod; Rahman, Md. Khalilur

doi:10.1016/j.envpol.2016.09.066

Cited by 52 publications

(31 citation statements)

References 42 publications

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“…These structural changes may be due to the increase of lipid peroxidation compounds in the erythrocytes (Bai et al, 2014;Ghaffar, Riaz, Ahrar, & Abbas, 2015). It is also well known that toxic substances damage the membrane shape, ion permeability and metabolism of cell, thus erythrocytes are structurally damaged (Sadiqul, Ferdous, Nannu, Mostakim, & Rahman, 2016). However, the frequencies of ENA and ECA were found to be decreased in the later days (day-14, -28 and -56) of exposure compare to initial days (day-7) in all salinity treated fish indicate that striped catfish might be adapted to the high salinity, especially at 4 and 8‰ salinity level.…”

Section: Discussionmentioning

confidence: 99%

Striped catfish ( Pangasianodon hypophthalmus ) could be suitable for coastal aquaculture

et al. 2019

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Summary Salinity intrusion in the coastal freshwater rivers due to climate change and construction of the dam in the upstream rivers are alarming in aquaculture. Hence, an experiment was conducted to know the effects of salinity on growth performance, hemato‐biochemical parameters and erythrocytes structure in a commercially cultivable catfish species, striped catfish (Pangasianodon hypophthalmus). Firstly, median lethal concentration (LC50) of salinity for striped catfish was determined and then the fish were exposed to three salinity conditions (4, 8 and 12‰) and a control (0‰). Fish were sacrificed at day 7, 14, 28 and 56 after the start of salinity exposure. The 96 hr LC50 value was found to be 14.87‰. Salinity levels from freshwater to 8‰ showed optimal conditions with high survival rate and good growth performances of fish in terms of weight gain and specific growth rate (SGR). Interestingly, the lowest food conversion ratio (FCR) was found in 4‰ group. The hemoglobin (Hb) level and number of red blood cells (RBCs) were found to be decreased significantly in 8 and 12‰ compared to 0 and 4‰ at the initial days of exposure, while number of white blood cells (WBCs) and glucose level showed opposite scenario. Frequencies of ENA (erythrocytic nuclear abnormalities) and ECA (erythrocytic cellular abnormalities) were significantly increased with increasing salinities in the initial days of exposure. Overall, findings of the present study revealed that striped catfish might be suitable fish species for culture in the brackish water containing salinity up to 10‰.

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Section: Discussionmentioning

confidence: 99%

Striped catfish ( Pangasianodon hypophthalmus ) could be suitable for coastal aquaculture

et al. 2019

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“…The development of micronuclei may be a marker of genomic harm. The micronuclei of fish are useful exploratory framework for evaluating the genotoxic attributes of chemicals prevailing in the aquatic ecosystem (Khan et al 2018;Sadiqul et al 2016;Bolognesi and Hayashi, 2011). Micronuclei were likewise answered to start out amid anaphase from slacking acentric chromosomes or chromatid sections produced through unrepaired DNA breakdowns or the misrepair of DNA breaks (Fenech et al 2011).…”

Section: Discussionmentioning

confidence: 99%

“…The intense assault of the chemical profenofos prompts erythrocytic layer disturbances and nuclear retrogressions in the experimental fish, specifically, micronuclei, binucleus, declined nucleus, notched nuclei, nuclear scaffold, and nuclear bud. Various investigations delineate the introduction of genotoxic substances and also the distance of varied NAE (Khan et al 2018;Sadiqul et al 2016;Ergene et al 2007;Barˇsiene et al 2006;Cavas and Ergene-Gozukara 2005;Kammann et al 2004). Pesticides delivered deeply responsive free radicals inside the fish body.…”

Section: Discussionmentioning

confidence: 99%

“…Nuclear irregularities of the erythrocyte (NAE) totally different from MN were ordered by Carrasco et al (1990). Architectural variations from the standard recognizable proof criteria of erythrocytes ought to be conflicting than the general erythrocyte cells structure which has an ovoid outline with a midway dense nucleus (Sadiqul et al 2016).…”

Section: Assessment Of Erythrocyte Deformitiesmentioning

confidence: 99%

“…The danger of pesticides to aquatic life forms can be investigated by assessing adjustments within the enzymological, hematological, and biochemical parameters (Saravanan et al 2011). Organophosphorus chemical causes many harmful consequences for fish erythrocytes at the nuclear and cellular levels (Sadiqul et al 2016). A few examinations are accessible for groupings of pesticides in the bodies of fish (James and Sampath 1996) that cause numerous alterations in blood parameters and changes to the erythrocytic nuclear and cellular structures (Sadiqul et al 2016;Svoboda et al 2001).…”

Section: Introductionmentioning

confidence: 99%

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Recuperation patterns in fish with reference to recovery of erythrocytes in Barbonymus gonionotus disordered by an organophosphate

Islam

Khan

Moniruzzaman

et al. 2019

Int. J. Environ. Sci. Technol.

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Organophosphate pesticides are extravagantly used in worldwide context to get rid of insects. Due to their relevance and edges in agriculture, organophosphate pesticide can effortlessly stretch to the aquatic ecological units and, correspondingly, cause threats to aquatic animals, like fish. Profenofos could be a diligent and cytotoxic organophosphate pesticide. Animals become liable to profenofos by means of water and food. Present experiment determines toxicological impacts of profenofos through the in vivo presentation of silver barb (Barbonymus gonionotus) to 1/10th and 1/2 of the median lethal concentration (LC 50) of profenofos as sublethal exposures for variable periods (7, 15, and 30 days). Succeeding recuperation arrays were additionally appraised yielding the exposed fish in tap water (without profenofos) for the identical time as they had been treated with profenofos. The study findings showed that, with the advancement of time and concentrations, treated fish demonstrated significantly (p < 0.05) bigger intensity of nuclear anomalies (nuclear aberrations of erythrocyte-NAE), for instance, micronucleus, swollen nucleus, terminal nucleus, extended nucleus, and karyopyknosis and, furthermore, cell variations from the standard structure of erythrocyte (cellular abnormalities of erythrocyte-CAE), for example, demembranated, crescentic, spindle-shaped, almond-formed, and twin-molded cells. Recuperation data showed that B. Gonionotus recovered spontaneously and the abnormal erythrocytic parameters were normalized with a concentration and durationdependent fashion. Thus, supported these knowledge, we tend to convert that erythrocytic variations (NAE and CAE) from the standard structure could fill in as an evaluation of the hazard caused by organophosphate pesticides on non-target living beings, notably fish.

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DNA damage induced by cylindrospermopsin on different tissues of the biomonitor fish Poecilia reticulata

Rabelo

Hanusch

Jesus

et al. 2021

Environmental Toxicology

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The cyanotoxin cylindrospermopsin (CYN) is the second biggest cause of poisoning worldwide, both in humans and animals. Although CYN primarily affects the aquatic environments and can be absorbed in fishes by multiple routes, data reporting its toxicity and mechanism of action are still scarce in this group. Using P. reticulata as model species, it was evaluated whether CYN promotes mutagenic and genotoxic effects in different fish target tissues. Adult females were exposed in a static way to 0 (control), 0.5, 1.0, and 1.5 μg L −1 of pure CYN for 24 and 96 hours. For the first time, DNA damage was detected in fish brain after CYN exposition. In brain cells, a concentrationresponse DNA damage was observed for both exposure times, suggesting a direct or indirect action of CYN in neurotoxicity. For the liver cells, 96 hours caused an increase in DNA damage, as well the highest percentage of DNA in the tail was reached when used 1.5 μg L −1 of CYN. In peripheral blood cells, an increase in DNA damage was observed for all tested concentrations after 96 hours. In erythrocytes, micronuclei frequency was higher at 1.5 μg L −1 treatment while the erythrocyte nuclear abnormalities (ENA) frequency was significantly higher even at the lowest CYN concentration. Such data demonstrated that acute exposition to CYN promotes genotoxicity in the brain, liver, and blood cells of P. reticulata, as well mutagenicity in erythrocytes. It rises an alert regarding to the toxic effects of CYN for aquatic organisms as well as for human health.

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Acute exposure to a quinalphos containing insecticide (convoy) causes genetic damage and nuclear changes in peripheral erythrocytes of silver barb, Barbonymus gonionotus

Cited by 52 publications

References 42 publications

Striped catfish ( Pangasianodon hypophthalmus ) could be suitable for coastal aquaculture

Striped catfish ( Pangasianodon hypophthalmus ) could be suitable for coastal aquaculture

Recuperation patterns in fish with reference to recovery of erythrocytes in Barbonymus gonionotus disordered by an organophosphate

DNA damage induced by cylindrospermopsin on different tissues of the biomonitor fish Poecilia reticulata

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