Acute fatty liver of pregnancy

Abstract

Acute fatty liver of pregnancy is a serious complication of the 3rd trimester associated with high rates of maternal-fetal morbidity and mortality. Prompt diagnosis and treatment are essential to achieve optimal maternal-fetal outcomes. Collaboration between critical-care and perinatal nursing staffs is a crucial component of managing patient care. A recent case of acute fatty liver of pregnancy is reported. A team approach resulted in the survival of the patient and the delivery of healthy twins.

First-Trimester Ultrasound

“…Thromboembolic disorders are major causes of morbidity and mortality in the pregnant patient. This is a rare condition, usually of the third trimester, complicating approximately 1 in 10,000 singleton gestations [ 254 ] but, of all the published cases, 14 % have been reported in twin gestations [ 255 ]. Other complications more common in women carrying multiple gestations, most likely secondary to increased levels of various hormones, in particular βHCG, include hyperemesis gravidarum [ 248 ]although this is not universally accepted as a more frequent complication in multiple pregnancies [ 249 ]-iron defi ciency anemia [ 250 ], intrahepatic cholestasis of pregnancy [ 251 ] and pruritic urticarial papules and plaques of pregnancy or PUPPP.…”