Acute fetal hypoxic bradycardia: solving the chemoreception puzzle

Thornburg, Kent L.

doi:10.1113/jp280529

Cited by 1 publication

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References 5 publications

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“…After PCP enters the human body, it circulates to the tissues and organs of the whole body, most of which are discharged from the urine, and about 20% can accumulate in the body. Relevant investigation shows that the content of PCP in residents in polluted areas is significantly increased compared with the control area; therefore, attention should be paid to the potential health harm of food residual PCP to human body [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Association of Pentachlorophenol with Fetal Risk of Prolonged Bradycardia: A Systematic Review and Meta-Analysis

Song

2022

Journal of Healthcare Engineering

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Objective. This study explored the systematic evaluation and meta-analysis of different concentrations of PCP on the risk of long-term bradycardia in fetuses. Methods. Cochrane Library, Embase, PubMed, China Biomedical Literature Service, CNCNKI, and Wanfang database were computerized to collect all case-control studies on the association between variety classes and different concentrations of environmental pollutant gas to fetal of prolonged bradycardia. After evaluating the quality of the inclusion study and extracting valid data, meta-analysis was performed using Stata15 software. Relative hazards were calculated using the Mantel-Haenszel method and the random effect model, and P values and I2 values were used for heterogeneity evaluation. When heterogeneity occurs, subgroup analysis and sensitivity analysis were used to explore the sources. Results. A total of 15 studies were included, including 1202 patients with fetal of prolonged bradycardia and 1380 in the control population. Meta-analysis showed that there was no statistical difference in PCP < 0.1 mg/L between the experimental group and control group (OR = 1.03, 95% CI (0.62, 1.72), P = 0.90 , I2 = 0%, Z = 0.13), but there was a statistical difference in PCP > 5 mg/L (OR = 1.73, 95% CI (1.15, 2.58), P = 0.008 , I2 = 0%, Z = 2.65), PCP > 10 mg/L (OR = 1.75, 95% CI (1.19, 2.57), P = 0.004 , I2 = 14%, Z = 2.85), and PCP >15 mg/L (OR = 2.02, 95% CI (1.38, 2.95), P = 0.0003 , I2 = 77%, Z = 3.61). Conclusion. In this study, we found that different concentrations of PCP increased the risk of long-term bradycardia in fetuses, and the risk coefficient increased with the increase of PCP concentration.

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Section: Introductionmentioning

confidence: 99%

Association of Pentachlorophenol with Fetal Risk of Prolonged Bradycardia: A Systematic Review and Meta-Analysis

Song

2022

Journal of Healthcare Engineering

View full text Add to dashboard Cite

show abstract

Acute fetal hypoxic bradycardia: solving the chemoreception puzzle

Cited by 1 publication

References 5 publications

Association of Pentachlorophenol with Fetal Risk of Prolonged Bradycardia: A Systematic Review and Meta-Analysis

Association of Pentachlorophenol with Fetal Risk of Prolonged Bradycardia: A Systematic Review and Meta-Analysis

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