Acute Gastrointestinal Bleeding Experience of a Specialized Management Team

Gostout, Christopher J.; Wang, Kenneth K.; Ahlquist, David A.; Clain, Jonathan E.; Hughes, Rollin W.; Larson, Mark V.; Petersen, Bret T.; Schroeder, Kenneth W.; Tremaine, William J.; Viggiano, Thomas R.; Balm, Rita K.

doi:10.1097/00004836-199204000-00014

Cited by 101 publications

(44 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, when compared to American studies (10,23) , we found fewer patients with gastritis (8.5% vs 13% and 23%, respectively). In respect to the diagnosis of gastritis, our diagnostic profile is similar to that found in European studies, but the prevalence of bleeding from varices is greater among our patients (17,22,28) .…”

Section: Discussioncontrasting

confidence: 80%

“…Although the use of NSAIDs is a well-established risk factor for upper gastrointestinal bleeding, we did not find any significantly correlation with the etiology of the hemorrhagic episode. Interestingly, in our series the previous use of NSAIDs was lower than that reported by others (10,21) . It is possible that this finding actually represents distinct characteristics of the populations, or that a bias may have occurred during retrospective data collection.…”

Section: Discussioncontrasting

confidence: 74%

“…It is possible that the prevalence of alcohol related liver disease and schistossomotic liver disease with portal hypertension might be increased in the population studied. Previous history of peptic ulcer disease was somewhat lower than that reported by others (10,28) . It is difficult to interpret the relevance of this latter finding because information about previous diseases also depends on the accessibility of the patients to the local health care system.…”

Section: Discussioncontrasting

confidence: 56%

“…Similarly to other surveys (8,10,17,22,27,28) the most common bleeding lesion identified at upper GI endoscopy was peptic ulcer disease, duodenal ulcer being more common than gastric ulcer. Nevertheless, when compared to American studies (10,23) , we found fewer patients with gastritis (8.5% vs 13% and 23%, respectively).…”

Section: Discussionsupporting

confidence: 55%

“…By the other hand, underlying liver disease was usually higher in our series as compared with others (4,10,28) . It is possible that the prevalence of alcohol related liver disease and schistossomotic liver disease with portal hypertension might be increased in the population studied.…”

Section: Discussioncontrasting

confidence: 50%

See 4 more Smart Citations

Upper gastrointestinal bleeding in a Brazilian hospital: a retrospective study of endoscopic records

Zaltman

Souza

et al. 2002

Arq. Gastroenterol.

View full text Add to dashboard Cite

-Background -Upper gastrointestinal bleeding is a frequent and potentially severe complication of most digestive diseases of the upper gastrointestinal tract. Upper endoscopy has a crucial role in the diagnosis and treatment of upper gastrointestinal bleeding, however epidemiological studies are still limited in our country. Aims -To assess the clinical characteristics, endoscopic accuracy, treatment efficiency and clinical outcome of patients admitted to the endoscopic unit with upper gastrointestinal bleeding. Methods -A retrospective study of consecutive records from patients who underwent emergency endoscopy for upper gastrointestinal bleeding was performed during a period of 2 years. Results -Most patients were male 68.7%, with a mean age of 54.5 ± 17.5 years. A bleeding site could be detected in 75.6% of the patients. Diagnostic accuracy was greater within the first 24 hours of the bleeding onset, and in the presence of hematemesis. Peptic ulcer was the main cause of upper gastrointestinal bleeding (35%). The prevalence of variceal bleeding (20.45%) indicates a high rate of underlying liver disease. Endoscopic treatment was performed in 23.86% of the patients. Permanent hemostasis was achieved in 86% of the patients at the first endoscopic intervention, and in 62.5% of the patients after rebleeding. Emergency surgery was seldom necessary. The average number of blood units was 1.44 ± 1.99 per patient. The average length of hospital stay was 7.71 ± 12.2 days. Rebleeding was reported in 9.1% of the patients. The overall mortality rate of 15.34% was significantly correlated with previous liver disease. Conclusions -Diagnostic accuracy was related to the time interval between the bleeding episode and endoscopy, and to clinical presentation. Endoscopic therapy was an effective tool for selected patients. The resulting increased duration of hospitalization and higher mortality rate in the patients submitted to therapeutic endoscopy were attributed to a higher prevalence of variceal bleeding and underlying liver disease.

show abstract

Section: Discussioncontrasting

confidence: 80%

Section: Discussioncontrasting

confidence: 74%

Section: Discussioncontrasting

confidence: 56%

Section: Discussionsupporting

confidence: 55%

Section: Discussioncontrasting

confidence: 50%

See 3 more Smart Citations

Upper gastrointestinal bleeding in a Brazilian hospital: a retrospective study of endoscopic records

Zaltman

Souza

et al. 2002

Arq. Gastroenterol.

View full text Add to dashboard Cite

show abstract

Lower GI Bleeding: Endoscopic, Radiological and Surgical Diagnosis and Management

Ignjatovic

Jenkins

Saunders

2011

Gastrointestinal Bleeding

View full text Add to dashboard Cite

Octreotide Therapy for Control of Acute Gastrointestinal Bleeding in Children

Eroglu,

Emerick,

Whitingon

et al. 2004

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

ObjectivesTo evaluate the outcomes of octreotide use in children with gastrointestinal bleeding with or without portal hypertension.MethodsThe medical charts of children who received continuous octreotide infusion for the indication of gastrointestinal bleeding from January 1995 to December 2000 were retrospectively reviewed.ResultsTwenty‐one children with portal hypertension received octreotide infusions (1–2 μg/kg/h) during 35 gastrointestinal bleeding episodes. The duration of infusion ranged from 19 hours to 7 days. Bleeding ceased in 71% of children. Post‐treatment rebleeding occurred in 52%, and the mortality was 19%. Response to octreotide, rebleeding, and mortality did not differ significantly between patients with or without intrinsic liver disease.Twelve children with gastrointestinal bleeding unrelated to portal hypertension received octreotide during 14 episodes. The duration of octreotide ranged from 3 hours to 36 days. Fifty percent of children had resolution of bleeding during the infusion. Post‐treatment rebleeding occurred in 29%, and the mortality was 50%. No major adverse events were observed in either group.ConclusionsA high rate of bleeding control was achieved with octreotide during acute gastrointestinal bleeding in children with portal hypertension. However, controlled studies are needed for more definitive description of its clinical effects. The role of octreotide is less clear in gastrointestinal bleeding unrelated to portal hypertension.

show abstract

Acute Gastrointestinal Bleeding Experience of a Specialized Management Team

Cited by 101 publications

References 0 publications

Upper gastrointestinal bleeding in a Brazilian hospital: a retrospective study of endoscopic records

Upper gastrointestinal bleeding in a Brazilian hospital: a retrospective study of endoscopic records

Lower GI Bleeding: Endoscopic, Radiological and Surgical Diagnosis and Management

Octreotide Therapy for Control of Acute Gastrointestinal Bleeding in Children

Contact Info

Product

Resources

About